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Table 1 List of proteins found to be perturbed in animals with active U. parvum infectiona).

From: Ureaplasma parvum infection alters filamin a dynamics in host cells

Accessionb)

Protein name

Gene Ontology Biological Processc)

Effectd)

IPI00194097.5

Gc Vitamin D-binding protein

transports vitamin D and its metabolites

IPI00193485.2

Isocitrate dehydrogenase [NADP]

carbohydrate metabolism

IPI00767147.1

Similar to Alpha-enolase

carbohydrate metabolism

IPI00195372.1

Elongation factor 1-alpha 1

protein biosynthesis/translational elongation

IPI00231358.6

Profilin - 1

actin binding

IPI00454431.1

Brain-specific alpha actinin 1

actin binding

IPI00365286.3

Similar to Vinculin

cell motility/cell adhesion/lamellipodium biogenesis

IPI00409539.3

Similar to Filamin-A

actin filament binding/actin cytoskeleton reorganization/glycoprotein binding/cytoplasmic sequestering of protein/regulation of transcription factor/regulation of I-kappa β kinase/NF-κβ cascade

  1. a) Proteins found to be significantly altered by both enrichment analysis (Figure 1A and B) and ANOVA (Figure 1b).
  2. b) Accession numbers refer to the International Protein Database, http://www.ebi.ac.uk/IPI/IPIhelp.html.
  3. c) Gene ontology data was obtained from the Panther database http://www.pantherdb.org and the UniprotKB/Swiss-Prot Database http://www.ebi.ac.uk/uniprot.
  4. d) Effect refers to the protein ratio that was generated by the ProGroup™ algorithm, which compared actively infected animals (UTI and Struvite groups) to Negative group or Control group. Actual protein ratios are listed in Additional file 1, tables S1 and S2.