Table 2 Anti-HBs antibody responses one month after HBV challenge by pre-vaccination status (ATP Cohort for immunogenicity)
Post challenge | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
≥ 3.3 mIU/ml | ≥ 10 mIU/ml | ≥ 100 mIU/ml | GMC | |||||||||
Pre-challenge status | N | n | % | 95% CI | n | % | 95% CI | n | % | 95% CI | value | 95% CI |
<3.3 mIU/ml | 21 | 19 | 90.5 | [69.6; 98.8] | 17 | 81.0 | [58.1; 94.6] | 11 | 52.4 | [29.8; 74.3] | 85.4 | [24.7; 295.0] |
≥ 3.3 mIU/ml | 264 | 264 | 100 | [98.6; 100] | 264 | 100 | [98.6; 100] | 262 | 99.2 | [97.3; 99.9] | 12524.1 | [9907.2; 15832.2] |
<10 mIU/ml | 42 | 40 | 95.2 | [83.8; 99.4] | 38 | 90.5 | [77.4; 97.3] | 31 | 73.8 | [58.0; 86.1] | 249.8 | [116.9; 534.1] |
≥ 10 mIU/ml | 243 | 243 | 100 | [98.5; 100] | 243 | 100 | [98.5; 100] | 242 | 99.6 | [97.7; 100] | 16010.1 | [12812.2; 20006.2] |
<100 mIU/ml | 151 | 149 | 98.7 | [95.3; 99.8] | 147 | 97.4 | [93.4; 99.3] | 139 | 92.1 | [86.5; 95.8] | 2119.3 | [1475.8; 3043.4] |
≥ 100 mIU/ml | 134 | 134 | 100 | [97.3; 100] | 134 | 100 | [97.3; 100] | 134 | 100 | [97.3; 100] | 42433.2 | [34084.1; 52827.5] |