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Table 3 Clinical utility of T-SPOT.TB in addition to AFB smear microscopy

From: Role of interferon-gamma release assays in the diagnosis of pulmonary tuberculosis in patients with advanced HIV infection

Test Result Likelihood Ratio Post-test Probability of
Tuberculosis
AFB Smear Positive Patients*   
T-SPOT.TB + 1.56 96%
T-SPOT.TB - 0.44 87%
AFB Smear Negative Patients   
T-SPOT.TB + 1.48 47%
T-SPOT.TB - 0.6 26%
  1. Abbreviations: AFB, acid-fast bacilli.
  2. * Pre-test probability of tuberculosis = 94% (tuberculosis prevalence in AFB smear positive patients)
  3. † Pre-test probability of tuberculosis = 37% (tuberculosis prevalence in AFB smear negative patients)