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Table 3 Variation of meropenem MIC and imipenem MIC results obtained by Etest method realized by local participants, and by agar dilution reference method realized by a centralized centre (anaerobes excluded).

From: Comparative in vitro activity of Meropenem, Imipenem and Piperacillin/tazobactam against 1071 clinical isolates using 2 different methods: a French multicentre study

 

% Variations from Agar Dilution Method MIC in log2 dilutions

Etest

VME

>-2

ME

-2

mE

-1

Same

mE

+1

ME

+2

VME

>+2

Log trend *

Meropenem n = 923

7

9

78

367

306

132

24

+0.5

(%)

(0.8)

(2.2)

(8.5)

(40)

(33)

(14)

(2.5)

 

Imipenem n = 923

5

12

37

210

312

273

74

+1.1

(%)

(0.5)

(1.3)

(4)

(22.7)

(33.5)

(29.7)

(8)

 
  1. * Trend in MIC when compared Etest/Agar dilution method
  2. VME: very major error - ME: major error - mE: minor error