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Table 3 Variation of meropenem MIC and imipenem MIC results obtained by Etest method realized by local participants, and by agar dilution reference method realized by a centralized centre (anaerobes excluded).

From: Comparative in vitro activity of Meropenem, Imipenem and Piperacillin/tazobactam against 1071 clinical isolates using 2 different methods: a French multicentre study

  % Variations from Agar Dilution Method MIC in log2 dilutions
Etest VME
>-2
ME
-2
mE
-1
Same mE
+1
ME
+2
VME
>+2
Log trend *
Meropenem n = 923 7 9 78 367 306 132 24 +0.5
(%) (0.8) (2.2) (8.5) (40) (33) (14) (2.5)  
Imipenem n = 923 5 12 37 210 312 273 74 +1.1
(%) (0.5) (1.3) (4) (22.7) (33.5) (29.7) (8)  
  1. * Trend in MIC when compared Etest/Agar dilution method
  2. VME: very major error - ME: major error - mE: minor error