From: Mortality among patients with tuberculosis requiring intensive care: a retrospective cohort study
Nonsurvivors (n = 44) | Survivors (n = 23) | p-value | |
---|---|---|---|
APACHE II score | 22.4 ± 6.9 | 23.4 ± 6.8 | 0.625 |
Early ICU admission | 10 (100) | 0 | 0.004 |
Presence of at least one symptom | 35 (81.4) | 21 (91.3) | 0.474 |
Pulmonary TB | 27 (61.4) | 18 (78.3) | 0.261 |
Isolated Pulmonary TB | 16 (36.4) | 8 (34.8) | 0.999 |
Isolated Extrapulmonary TB | 16 (36.4) | 5 (21.7) | 0.343 |
Pulmonary + Extrapulmonary TB | 12 (27.3) | 10 (43.5) | 0.286 |
Cavitary disease | 3 (6.8) | 2 (8.7) | 0.999 |
Milliary radiological pattern | 2 (4.5) | 6 (26.1) | 0.016 |
Smear-positive sputum | 10 (38.5) | 15 (75.0) | 0.030 |
Delayed diagnosis | 14 (33.3) | 7 (31.8) | 0.999 |
WBC > 12000 mm-3 | 11 (25.0) | 2 (8.7) | 0.192 |
Rifampicin-based regimens | 44 (100) | 20 (87.0) | 0.037 |
Hepatotoxicity during hospitalization | 5 (11.4) | 6 (26.1) | 0.167 |
Mechanical ventilation | 41 (93.2) | 21 (91.3) | 0.999 |
Duration of mechanical ventilation, d | 5 (2-15) | 9.5 (3.75-21.3) | 0.228 |
Sepsis | 43 (97.7) | 21 (93.3) | 0.269 |
Septic shock | 39 (88.6) | 17 (73.9) | 0.167 |
ARDS | 5 (11.4) | 4 (17.4) | 0.481 |
Ventilator-associated pneumonia | 9 (20.5) | 11 (47.8) | 0.041 |
Acute renal failure | 17 (38.6) | 4 (17.4) | 0.133 |
Multiple organ failure | 37 (84.1) | 21 (91.3) | 0.708 |