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Table 4 Multivariate GEE regression models of testing intervals and of probability of >9 and >6 months between viral load measurements

From: Regional differences in rates of HIV-1 viral load monitoring in Canada: Insights and implications for antiretroviral care in high income countries

  Interval (days) between successive tests Probability of an interval >9 months Probability of an interval >6 months
Covariates Estimate (95% CI) p value Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value
Intercept 125.8 (118.8, 132.9) < .0001 0.09 (0.07, 0.11) < .0001 0.20 (0.16, 0.23) < .0001
Region       
   Quebec 20.3 (15.5, 25.0) < .0001 1.72 (1.39, 2.14) < .0001 1.61 (1.37, 1.89) < .0001
   Ontario 18.7 (14.3, 23.0) < .0001 1.78 (1.37, 2.31) < .0001 1.77 (1.47, 2.14) < .0001
   BC 0   1   1  
Age (per 10 years) -3.8 (-5.4, -2.2) < .0001 0.77 (0.70, 0.85) < .0001 0.77 (0.72, 0.83) < .0001
Risk factor       
   MSM -9.2 (-13.1, -5.4) < .0001 0.62 (0.49, 0.78) < .0001 0.66 (0.56, 0.77) < .0001
   IDU 16.0 (11.1, 20.9) < .0001 1.68 (1.38, 2.05) < .0001 1.71 (1.48, 1.99) < .0001
Year of initiating cART       
   >2004 -15.8 (-21.9, -9.7) < .0001 0.62 (0.46, 0.83) 0.001 0.74 (0.60, 0.91) 0.005
   2001-2004 -12.4 (-18.2, -6.6) < .0001 0.70 (0.57, 0.86) 0.0006 0.75 (0.64, 0.89) 0.0007
   2000 (ref.) 0   1   1  
1st year of cART -24.3 (-26.0, -22.6) < .0001 0.15 (0.12, 0.20) < .0001 0.32 (0.29, 0.36) < .0001
On cART at current visit -27.8 (-31.0, -24.6) < .0001 0.34 (0.29, 0.40) < .0001 0.40 (0.36, 0.45) < .0001
VL < 50 copies/mL at previous test 8.6 (6.6, 10.7) < .0001 0.56 (0.48, 0.65) < .0001 0.90 (0.82, 0.98) 0.02
Boosted PI based cART -9.1 (-12.2, -6.0) < .0001    0.82 (0.71, 0.94) 0.006
AIDS defining illness -4.9 (-8.5, -1.4) 0.007     
  1. MSM = men who have sex with men, IDU = injection drug use, cART = combination antiretroviral therapy, VL = viral load, PI = protease inhibitor,.