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Table 1 Comparison of Baseline Demographic and Clinical Characteristics by Region

From: Regional differences in rates of HIV-1 viral load monitoring in Canada: Insights and implications for antiretroviral care in high income countries

  

Region

 

Characteristics

Total (n = 3648)

BC (n = 1674)

Ontario (n = 1143)

Quebec (n = 831)

p value

Age

40 (34-46)

40 (34-47)

39 (34-45)

40 (34-46)

< 0.01

Male

2925 (80%)

1328 (79%)

934 (82%)

663 (80%)

0.28

Race†

     

   Caucasian

956 (52%)

552 (45%)

309 (50%)

95 (84%)

< 0.0001

   Black

181 (10%)

31 (3%)

138 (26%)

12 (11%)

 

   First Nation

121 (7%)

103 (9%)

15 (3%)

3 (3%)

 

   Mixed

465 (25%)

464 (38%)

1 (<%

0 (0%)

 

   Other

128 (7%)

66 (5%)

59 (11%)

3 (3%)

 

   Missing

1837

497

622

718

 

Risk factor‡

     

   MSM

1015 (34%)

203 (12%)

362 (66%)

450 (60%)

< 0.0001

   IDU

632 (21%)

442 (26%)

82 (13%)

108 (14%)

< 0.0001

   Heterosexual

486 (16%)

98 (6%)

188 (35%)

200 (27%)

< 0.0001

   Endemic country

233 (19%)

0 (0%)

92 (20%)

141 (19%)

0.52

   Blood product recipient

43 (1%)

10 (1%)

25 (6%)

8 (1%)

< 0.0001

   Other/Missing

1554 (43%)

961 (57%)

569 (45%)

147 (9%)

< 0.0001

AIDS defining illness

481 (13%)

259 (15%)

115 (10%)

107 (13%)

< 0.001

cART initiation date

2003 (2001-05)

2003 (2001-05)

2004 (2002 - 05)

2004 (2002-05)

< 0.0001

Type of cART

     

   NNRTI-based

1586 (43%)

753 (45%)

512 (45%)

321 (39%)

< 0.0001

   Boosted PI-based

1433 (39%)

726 (43%)

397 (35%)

310 (37%)

 

   Single PI-based

384 (11%)

151 (9%)

137 (12%)

96 (12%)

 

   Other cART

245 (7%)

44 (3%)

97 (8%)

104 (13%)

 

CD4 count (cells/mm3)

190 (100-277)

170 (80-260)

202 (107-296)

208 (127-290)

< 0.0001

CD4 count category

     

   < 200 cells/mm3

1921 (53%)

981 (59%)

555 (49%)

385 (47%)

< 0.0001

   200 - 350 cells/mm3

1175 (32%)

486 (29%)

374 (33%)

315 (38%)

 

   > 350 cells/mm3

544 (15%)

207 (12%)

212 (19%)

125 (15%)

 

VL (log10 copies/mL)

4.9 (4.4-5.1)

5.0 (4.6-5.0)

4.8 (4.3-5.3)

4.8 (4.2-5.2)

< 0.01

VL <50 copies/mL

139 (4%)

56 (3%)

48 (4%)

35 (4%)

0.40

Hepatitis C co-infection

736 (30%)

501 (44%)

124 (22%)

111 (15%)

< 0.0001

  1. MSM = men who have sex with men, IDU = injection drug user, cART = combination antiretroviral therapy, NNRTI = non nucleoside reverse transcriptase inhibitor, PI = protease inhibitor, VL = viral load.
  2. †Race percentages are calculated as percentages of non-missing values. ‡Risk factors are not mutually exclusive. Results are N (%) or median (interquartile range). Missing values are only reported for variables with more than 25% missing data.
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BMC Infectious Diseases

ISSN: 1471-2334

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