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Table 1 Comparison of Baseline Demographic and Clinical Characteristics by Region

From: Regional differences in rates of HIV-1 viral load monitoring in Canada: Insights and implications for antiretroviral care in high income countries

   Region  
Characteristics Total (n = 3648) BC (n = 1674) Ontario (n = 1143) Quebec (n = 831) p value
Age 40 (34-46) 40 (34-47) 39 (34-45) 40 (34-46) < 0.01
Male 2925 (80%) 1328 (79%) 934 (82%) 663 (80%) 0.28
Race†      
   Caucasian 956 (52%) 552 (45%) 309 (50%) 95 (84%) < 0.0001
   Black 181 (10%) 31 (3%) 138 (26%) 12 (11%)  
   First Nation 121 (7%) 103 (9%) 15 (3%) 3 (3%)  
   Mixed 465 (25%) 464 (38%) 1 (<% 0 (0%)  
   Other 128 (7%) 66 (5%) 59 (11%) 3 (3%)  
   Missing 1837 497 622 718  
Risk factor‡      
   MSM 1015 (34%) 203 (12%) 362 (66%) 450 (60%) < 0.0001
   IDU 632 (21%) 442 (26%) 82 (13%) 108 (14%) < 0.0001
   Heterosexual 486 (16%) 98 (6%) 188 (35%) 200 (27%) < 0.0001
   Endemic country 233 (19%) 0 (0%) 92 (20%) 141 (19%) 0.52
   Blood product recipient 43 (1%) 10 (1%) 25 (6%) 8 (1%) < 0.0001
   Other/Missing 1554 (43%) 961 (57%) 569 (45%) 147 (9%) < 0.0001
AIDS defining illness 481 (13%) 259 (15%) 115 (10%) 107 (13%) < 0.001
cART initiation date 2003 (2001-05) 2003 (2001-05) 2004 (2002 - 05) 2004 (2002-05) < 0.0001
Type of cART      
   NNRTI-based 1586 (43%) 753 (45%) 512 (45%) 321 (39%) < 0.0001
   Boosted PI-based 1433 (39%) 726 (43%) 397 (35%) 310 (37%)  
   Single PI-based 384 (11%) 151 (9%) 137 (12%) 96 (12%)  
   Other cART 245 (7%) 44 (3%) 97 (8%) 104 (13%)  
CD4 count (cells/mm3) 190 (100-277) 170 (80-260) 202 (107-296) 208 (127-290) < 0.0001
CD4 count category      
   < 200 cells/mm3 1921 (53%) 981 (59%) 555 (49%) 385 (47%) < 0.0001
   200 - 350 cells/mm3 1175 (32%) 486 (29%) 374 (33%) 315 (38%)  
   > 350 cells/mm3 544 (15%) 207 (12%) 212 (19%) 125 (15%)  
VL (log10 copies/mL) 4.9 (4.4-5.1) 5.0 (4.6-5.0) 4.8 (4.3-5.3) 4.8 (4.2-5.2) < 0.01
VL <50 copies/mL 139 (4%) 56 (3%) 48 (4%) 35 (4%) 0.40
Hepatitis C co-infection 736 (30%) 501 (44%) 124 (22%) 111 (15%) < 0.0001
  1. MSM = men who have sex with men, IDU = injection drug user, cART = combination antiretroviral therapy, NNRTI = non nucleoside reverse transcriptase inhibitor, PI = protease inhibitor, VL = viral load.
  2. †Race percentages are calculated as percentages of non-missing values. ‡Risk factors are not mutually exclusive. Results are N (%) or median (interquartile range). Missing values are only reported for variables with more than 25% missing data.