| | |
Region
| |
|---|
|
Characteristics
|
Total (n = 3648)
|
BC (n = 1674)
|
Ontario (n = 1143)
|
Quebec (n = 831)
|
p value
|
|---|
|
Age
|
40 (34-46)
|
40 (34-47)
|
39 (34-45)
|
40 (34-46)
|
< 0.01
|
|
Male
|
2925 (80%)
|
1328 (79%)
|
934 (82%)
|
663 (80%)
|
0.28
|
|
Race†
| | | | | |
|
Caucasian
|
956 (52%)
|
552 (45%)
|
309 (50%)
|
95 (84%)
|
< 0.0001
|
|
Black
|
181 (10%)
|
31 (3%)
|
138 (26%)
|
12 (11%)
| |
|
First Nation
|
121 (7%)
|
103 (9%)
|
15 (3%)
|
3 (3%)
| |
|
Mixed
|
465 (25%)
|
464 (38%)
|
1 (<%
|
0 (0%)
| |
|
Other
|
128 (7%)
|
66 (5%)
|
59 (11%)
|
3 (3%)
| |
|
Missing
|
1837
|
497
|
622
|
718
| |
|
Risk factor‡
| | | | | |
|
MSM
|
1015 (34%)
|
203 (12%)
|
362 (66%)
|
450 (60%)
|
< 0.0001
|
|
IDU
|
632 (21%)
|
442 (26%)
|
82 (13%)
|
108 (14%)
|
< 0.0001
|
|
Heterosexual
|
486 (16%)
|
98 (6%)
|
188 (35%)
|
200 (27%)
|
< 0.0001
|
|
Endemic country
|
233 (19%)
|
0 (0%)
|
92 (20%)
|
141 (19%)
|
0.52
|
|
Blood product recipient
|
43 (1%)
|
10 (1%)
|
25 (6%)
|
8 (1%)
|
< 0.0001
|
|
Other/Missing
|
1554 (43%)
|
961 (57%)
|
569 (45%)
|
147 (9%)
|
< 0.0001
|
|
AIDS defining illness
|
481 (13%)
|
259 (15%)
|
115 (10%)
|
107 (13%)
|
< 0.001
|
|
cART initiation date
|
2003 (2001-05)
|
2003 (2001-05)
|
2004 (2002 - 05)
|
2004 (2002-05)
|
< 0.0001
|
|
Type of cART
| | | | | |
|
NNRTI-based
|
1586 (43%)
|
753 (45%)
|
512 (45%)
|
321 (39%)
|
< 0.0001
|
|
Boosted PI-based
|
1433 (39%)
|
726 (43%)
|
397 (35%)
|
310 (37%)
| |
|
Single PI-based
|
384 (11%)
|
151 (9%)
|
137 (12%)
|
96 (12%)
| |
|
Other cART
|
245 (7%)
|
44 (3%)
|
97 (8%)
|
104 (13%)
| |
|
CD4 count (cells/mm3)
|
190 (100-277)
|
170 (80-260)
|
202 (107-296)
|
208 (127-290)
|
< 0.0001
|
|
CD4 count category
| | | | | |
|
< 200 cells/mm3
|
1921 (53%)
|
981 (59%)
|
555 (49%)
|
385 (47%)
|
< 0.0001
|
|
200 - 350 cells/mm3
|
1175 (32%)
|
486 (29%)
|
374 (33%)
|
315 (38%)
| |
|
> 350 cells/mm3
|
544 (15%)
|
207 (12%)
|
212 (19%)
|
125 (15%)
| |
|
VL (log10 copies/mL)
|
4.9 (4.4-5.1)
|
5.0 (4.6-5.0)
|
4.8 (4.3-5.3)
|
4.8 (4.2-5.2)
|
< 0.01
|
|
VL <50 copies/mL
|
139 (4%)
|
56 (3%)
|
48 (4%)
|
35 (4%)
|
0.40
|
|
Hepatitis C co-infection
|
736 (30%)
|
501 (44%)
|
124 (22%)
|
111 (15%)
|
< 0.0001
|
- MSM = men who have sex with men, IDU = injection drug user, cART = combination antiretroviral therapy, NNRTI = non nucleoside reverse transcriptase inhibitor, PI = protease inhibitor, VL = viral load.
- †Race percentages are calculated as percentages of non-missing values. ‡Risk factors are not mutually exclusive. Results are N (%) or median (interquartile range). Missing values are only reported for variables with more than 25% missing data.
