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Table 3 Concordance and agreement between TST, T-SPOT.TB and QFN-G-IT results according BCG vaccination status*

From: IFN-γ response on T-cell based assays in HIV-infected patients for detection of tuberculosis infection

 

TST vs T-SPOT.TB

TST vs QFN-G-IT

T-SPOT.TB vs QFN-G-IT

 

Concordance (%)

κ (SE**)

Concordance (%)

κ (SE)

Concordance (%)

κ (SE)

HIV-positive

      

Overall

59/73 (80.8)

0.019 (0.123)

65/73 (89)

0.373 (0.173)

65/73 (89)

0.275 (0.184)

BCG

4/8 (50)

-***

4/8 (50)

-***

8/8 (100)

-***

Non-BCG

55/65 (84.6)

0.085 (0.154)

61/65 (93.8)

0.567 (0.194)

57/65 (87.7)

0.268 (0.186)

  1. * Indeterminate IFN-γ assays results were not included in the analysis.
  2. ** standard deviation
  3. ***κ value is not possible to calculate because of T-SPOT.TB and QFN-G-IT results are one constant variable.