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Table 2 Variables studied in univariate analysis and their association with the development of any postoperative infection (n = 13) and with development of post-operative SSI (n = 10).

From: Ampicillin/Sulbactam versus Cefuroxime as antimicrobial prophylaxis for cesarean delivery: a randomized study

Variable Post-op. Infection
n = 13 (7.4)
No Infection
n = 163 (92.6)
P Post-op. SSI
n = 10 (5.7)
No SSI
n = 166 (94.3)
P
Age, median (IQR) 27 (24-32) 28 (24-32) 1 28 (23-32) 28 (24-32) 1
Multiparity, n (%) 7 (53.8) 91 (55.8) 1 6 (60) 92 (55.4)  
BMI >25 kg/m2, n (%) 13 (100) 124 (76.1) 0.08 10 (100) 127 (76.5) 0.12
BMI ≥ 30 kg/m2, n (%) 7 (53.8) 69 (42.3) 0.6 5 (5) 71 (42.8) 0.7
Diabetes mellitus, n (%) 0 (0) 7 (4.3) 1 0 (0) 7 (4.2) 1
Hypertension/other CVD, n (%) 0 (0) 36 (22.1) 0.07 0 (0) 36 (21.7) 0.2
Chronic respiratory disease, n (%) 0 (0) 1 (0.6) 0.9 0 (0) 1 (0.6) 1
Corticosteroid use, n (%) 0 (0) 2 (1.2) 1 0 (0) 2 (1.2) 1
Creatinine in mg/dL, median (IQR) 0.6 (0.5-0.85) 0.6 (0.5-0.7) 0.2 0.7 (0.5-0.8) 0.6 (0.5-0.7) 0.2
ASA ≥ 2, n (%) 7 (53.8) 52 (31.9) 0.1 5 (50) 54 (32.5) 0.3
Regular prenatal f/u, n (%) 11 (84.6) 156 (96.9) 0.09 8 (80) 159 (97) 0.05*
Vaginal examinations >1, n (%) 9 (69.2) 87 (53.4) 0.4 8 (80) 88 (53) 0.11
Vaginal examinations ≥ 6, n (%) 6 (46.2) 17 (10.4) 0.002* 5 (50) 18 (10.8) 0.004*
Ruptured membranes, n (%) 7 (53.8) 47 (28.8) 0.1 6 (60) 48 (28.9) 0.07
Ruptured membranes ≥ 6 hours, n (%) 2 (15.4) 7 (4.3) 0.1 2 (20) 7 (4.2) 0.08
Non-elective cesarean, n (%) 9 (69.2) 78 (47.9) 0.2 8 (80) 79 (47.6) 0.056
Type of anesthesia (general vs. regional), n of general (%) 5 (38.5) 105 (64.4) 0.08 2 (20) 108 (65.1) 0.006*
Duration of surgery >60 minutes, n (%) 10 (76.9) 101 (62) 0.4 7 (70) 104 (62.7) 0.7
Blood loss >500 ml, n (%) 10 (76.9) 64 (39.3) 0.016* 8 (80) 66 (39.8) 0.018*
Duration of hospitalization in days, median (IQR) 5 (4-8) 4 (4-4) <0.001* 5 (4-8) 4 (4-4) <0.001*
  1. *: Significant associations p < 0.05. ASA: American society of Anesthesiologists score, BMI: Body mass index, CVD: Cardiovascular disease, Post-op: postoperative, IQR: Interquartile range