Table 2 Time of occurrence of first hypoglycaemia episode and hypoglycaemia severity
From: Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage
| Â | 2002-2006 cohort: Quinine 15 mg/kg regimen | 2006-2009 cohort: Quinine 20 mg/kg regimen | ||
|---|---|---|---|---|
Time period | Frequency by first episode (n = 145) n (%) | Frequency by all episodes (n = 229) n (%) | Frequency by first episode (n = 42) n (%) | Frequency by all episodes (n = 86) n (%) |
0 - 24 hrs | 118 (81) | 157 (69) | 30 (71) | 47 (55) |
After 24 hrs | 19 (13) | 41 (18) | 6 (14) | 21 (24) |
After 48 hrs | 8 (6) | 31 (14) | 6 (14) | 18(21) |
Severity (Blood glucose levels), n/N (%) | ||||
< 2.2 mmol/l | 74/954 (8) | 13/283(5) | P = 0.07 | |
< 2.5 mmol/l | 103/954 (11) | 22/283(8) | P = 0.14 | |
< = 3.0 mmol/l | 145/954 (15) | 42/283(15) | P = 1.00 | |
Final outcome (death) - those with and those without any hypoglycaemia post admission, n/N (%) | ||||
Hypoglycaemia = Yes | 29/145 (20) | 15/42 (36) | P = 0.04 | |
Hypoglycaemia = No | 73/809 (9) | 13/240 (5) | P = 0.07 | |
Final outcome (death) - those with and those without any hypoglycaemia at or during admission, n/N (%) | ||||
Hypoglycaemia = Yes | 45/155 (29) | 11/26 (42) | P = 0.18 | |
Hypoglycaemia = No | 57/797 (7) | 17/255 (7) | P = 1.00 | |