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Table 2 Time of occurrence of first hypoglycaemia episode and hypoglycaemia severity

From: Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage

  2002-2006 cohort: Quinine 15 mg/kg regimen 2006-2009 cohort: Quinine 20 mg/kg regimen
Time period Frequency by first episode (n = 145)
n (%)
Frequency by all episodes (n = 229)
n (%)
Frequency by first episode (n = 42)
n (%)
Frequency by all episodes (n = 86)
n (%)
0 - 24 hrs 118 (81) 157 (69) 30 (71) 47 (55)
After 24 hrs 19 (13) 41 (18) 6 (14) 21 (24)
After 48 hrs 8 (6) 31 (14) 6 (14) 18(21)
Severity (Blood glucose levels), n/N (%)
< 2.2 mmol/l 74/954 (8) 13/283(5) P = 0.07
< 2.5 mmol/l 103/954 (11) 22/283(8) P = 0.14
< = 3.0 mmol/l 145/954 (15) 42/283(15) P = 1.00
Final outcome (death) - those with and those without any hypoglycaemia post admission, n/N (%)
Hypoglycaemia = Yes 29/145 (20) 15/42 (36) P = 0.04
Hypoglycaemia = No 73/809 (9) 13/240 (5) P = 0.07
Final outcome (death) - those with and those without any hypoglycaemia at or during admission, n/N (%)
Hypoglycaemia = Yes 45/155 (29) 11/26 (42) P = 0.18
Hypoglycaemia = No 57/797 (7) 17/255 (7) P = 1.00