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Table 3 Relative rates* of type-specific and combined HPV infection clearance according to viral load

From: Human papillomavirus (HPV) types 16, 18, 31, 45 DNA loads and HPV-16 integration in persistent and transient infections in young women

    Relative rate (95%CI)
HPV type Viral load tertile No. of Events/No. Eligible cases Unadjusted Adjusted
16 Third 5/27 1.0 1.0
  Second 8/27 1.52 (0.49-4.69) 1.31 (0.41-4.20)
  First 13/27 2.55 (0.90-7.24) 2.38 (0.82-6.89)
18 Third 4/13 1.0 1.0
  Second 3/13 1.64 (0.31-8.78) 1.14 (0.18-7.35)
  First 11/13 4.76 (1.23-18.45) 4.61 (1.17-18.05)
31 Third 6/10 1.0 1.0
  Second 3/10 0.87 (0.21-3.69) 0.80 (0.19-3.44)
  First 2/9 0.67 (0.16-2.75) 0.66 (0.15-2.97)
45 Third 3/6 1.0 1.0
  Second 4/6 1.99 (0.21-19.02) 1.59 (0.15-16.91)
  First 3/6 2.25 (0.20-25.09) 2.06 (0.17-24.27)
Above HPV types combined Third 20/55 1.0 1.0
  Second 22/55 1.45 (0.79-2.64) 1.49 (0.81-2.74)
  First 24/56 2.11 (1.16-3.86) 2.21 (1.19-4.10)
  1. * Using Cox proportional hazards regression. Rate of clearance for third viral load tertile (highest) taken as referent. For the analysis of combined types the observations are not independent and required a robust variance estimator. Adjusted relative rates were estimated in models that included age and sexual partners as covariates.