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Table 2 Comparison of episodes of acute community-acquired Lm meningitis versus other aetiologies

From: Three-year multicenter surveillance of community-acquired listeria monocytogenes meningitis in adults

 

Listeria monocytogenes (n = 43)

Other agents (n = 232)

p

Age (median ± IQR)

69 ± 30

56 ± 33

0.019

Gender (male)

24 (56) d

128 (55)

0.938

Immunocompromised

29 (67)

86 (37)

<0.001

Previous otitis

1 (2.1)

43 (19.5)

0.005

Fever

39 (91)

186 (84)

0.246

Headache

29 (67)

166 (77)

0.146

Vomiting

20 (46)

132 (57)

0.070

Neck stiffness

30 (70)

167 (72)

0.204

Classic Triad a

21 (49)

90 (39)

0.533

GCS b at admission (median ± IQR)

13 ± 4

12 ± 4

0.664

Seizures

4 (9)

17 (7)

0.688

Focal neurological deficit

14 (32)

27 (12)

0.022

Cerebellum dysfunction

5 (12)

5 (2)

<0.001

Hyponatremia

19 (44)

60 (26)

0.066

Duration of symptoms in hours (median ± IQR)

70 ± 53

48 ± 53

0.07

WBC count CSF c (median ± IQR)

550 ± 2480

2860 ± 9380

0.007

CSF neutrophils ( median±IQR)

70 ± 59

90 ± 13

<0.001

CSF/blood glucose (median ± IQR)

0.26 ± 0.24

0.09 ± 0.26

<0.001

Protein level g/L ( median ± IQR)

2.0 ± 1.96

3.68 ± 5.53

<0.001

Mortality

12 (29)

36 (16)

0.059

  1. a Triad of fever, neck stiffness and change in mental status.
  2. b GCS: Glasgow Coma Scale.
  3. c CSF: Cerebrospinal Fluid.
  4. d Results are expressed as n (%) unless otherwise specified