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Table 3 MICs of penicillin and tetracycline for N. gonorrhoeae isolates

From: Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China

Site mutations* Serotypes Cases (n) MICs (mg/L)
    Penicillin Tetracycline
G120K/A121D IB3 56 2-4 2-8
  IB3/6 27 2-4 2-8
  IB3/6-IB2 44 2-4 2-8
  IB2-IB4-IB2 8 2-4 2-4
G120K/A121G IB3/6 19 2-4 2-8
G120N/A121D IB3/6-IB2 9 2 2-4
G120D IB4 25 2-4 2-8
G120K IB3/6-IB2 9 2-4 2-8
G120N/A121 and N122 deletion IB3/6-IB2 15 4-8 4-16
G120G/A121A IB3/6 3 0.12 0.25
  IB3 2 0.25 0.25
D120D/G121G IA6 87 0.06-0.5 0.06-0.5
D120G/G121G IA6 11 0.12-0.25 0.12-1
  1. *: G, K, A, D and N indicate glycine, lysine, aspartic acid and asparagine, respectively.