Skip to main content

Table 3 MICs of penicillin and tetracycline for N. gonorrhoeae isolates

From: Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China

Site mutations*

Serotypes

Cases (n)

MICs (mg/L)

   

Penicillin

Tetracycline

G120K/A121D

IB3

56

2-4

2-8

 

IB3/6

27

2-4

2-8

 

IB3/6-IB2

44

2-4

2-8

 

IB2-IB4-IB2

8

2-4

2-4

G120K/A121G

IB3/6

19

2-4

2-8

G120N/A121D

IB3/6-IB2

9

2

2-4

G120D

IB4

25

2-4

2-8

G120K

IB3/6-IB2

9

2-4

2-8

G120N/A121 and N122 deletion

IB3/6-IB2

15

4-8

4-16

G120G/A121A

IB3/6

3

0.12

0.25

 

IB3

2

0.25

0.25

D120D/G121G

IA6

87

0.06-0.5

0.06-0.5

D120G/G121G

IA6

11

0.12-0.25

0.12-1

  1. *: G, K, A, D and N indicate glycine, lysine, aspartic acid and asparagine, respectively.