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Table 2 G120 and A121 mutations in PorB1A and PorB1B of N. gonorrhoeae isolates*

From: Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China

Serotypes Cases (n) Site mutation patterns (n)
   G120K/A121D G120K/A121G G120N/A121D G120D/A121G G120D G120K G120N A121G
IB3 56 56 0 0 0 0 0 0 0
IB3/6 46 27 19 0 0 0 0 0 0
IB4 25 0 0 0 0 25 0 0 0
IB3/6-IB2 62 44 0 9 0 0 9 0 0
IB3/6-IB2# 15 0 0 0 0 0 0 15 0
IB2-IB4-IB2 8 8 0 0 0 0 0 0 0
IA6 98 0 0 0 87 0 0 0 11
Total 310 135 19 9 87 25 9 15 11
  1. *: 5 isolates (3 for IB3/6 and 2 for IB3 serotypes) without G120 and A121 mutations not included. G, K, A, D and N indicate glycine, lysine, aspartic acid and asparagine, respectively. #: isolates with deletions of both A121 and N122.