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Table 1 Characteristics and demographics of immunological responders and non-responders.

From: Long-term mortality in HIV patients virally suppressed for more than three years with incomplete CD4 recovery: A cohort study

Characteristics Immunologic responders Immunologic non-responders P
  N = 236 N = 55  
Male gender 179 (75.8) 48 (87.3) 0.065
Age at time of index date, median (IQR), years 37.6 (32.1 - 45.3) 42.6 (36.1 - 51.3) <0.001
Caucasians 171 (72.5) 47 (85.5) 0.045
Route of HIV infection    0.059
   Men who have sex with men 97 (41.1) 29 (52.7)  
   Heterosexually infected 98 (41.5) 14 (25.5)  
   Injection drug user 14 (5.9) 7 (12.7)  
   Other 26 (11.8) 3 (6.1)  
Chronic HCV infection 20 (8.5) 8 (14.5) 0.169
Cancer within 13 years prior to index date 27 (11.4) 10 (18.2) 0.177
One or more AIDS defining events prior to index date 114 (48.3) 24 (43.6) 0.532
One or more AIDS defining events after index date 3 (1.3) 2 (3.6) 0.240
Diagnosed with HIV before 1 January 1995 94 (49.8) 27 (49.1) 0.210
Treated with zidofovir prior to index date 219 (92.8) 54 (98.2) 0.465
Nadir CD4 cell count, median (IQR), cells/μL 40 (10 - 82) 40 (15 - 57) 0.289
More than one year from first CD4 cell count ≤ 200 cells/μL to start of the virologically suppressed period* 96 (40.7) 32 (58.2) 0.019
Time from start of HAART to start of the virologically suppressed period, median (IQR), years 0.4 (0.2 - 1.1) 0.4 (0.3 - 1.3) 0.518
  1. * Median time from first CD4 cell count ≤ 200 cells/μL to start of the virologically suppressed period was 0.7 year (IQR; 0.3 - 2.2) for IRs and 1.5 years (IQR; 0.4 - 3.2) for INRs.