Spiral ligament fibrocyte-derived MCP-1/CCL2 contributes to inner ear inflammation secondary to nontypeable H. influenzae-induced otitis media

Table 1 NTHI-induced inner ear inflammation in wild type, MCP-1-deficient and CCR2-deficient mice.

Mice	Inoculation (mice)	No inflammation (ears)	Serous labyrinthitis (ears)	Purulent labyrinthitis (ears)	Fisher's exact test
Wild type	Saline^a (4)	4	2	2
	NTHI^b (7)	1	3	10	a vs. b: p < 0.05
MCP-1^-/-	NTHI^c (5)	0	4	6	b vs. c: NS
CCR2^-/-	NTHI^d (5)	0	0	10	b vs. d: NS

ISSN: 1471-2334