Skip to main content

Table 4 Predictive values of the cirrhosis algorithm and of liver biopsy, FibroScan and FibroTest for the prediction of HCV-related severe events occurrence, ANRS CO 13 HEPAVIH cohort of HIV-HCV co-infected patients

From: The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): Early findings, 2006-2010

  

HCV-related severe eventsa

  
  

Absence (n)

Presence (n)

PPV (%)

NPV (%)

Algorithm* N=987

Absence of cirrhosis

752

4

12.5

99.5

 

Presence of cirrhosis

203

29

  

Liver Biopsy N=192

Metavir < F4

161

2

10.3

98.8

 

Metavir F4

26

3

  

FibroScan N=806

<12.5KPa

653

4

7.4

99.4

 

≤ 12.5 KPa

138

11

  

FibroTest N=718

Metavir < F4

528

7

8.2

98.7

 

Metavir F4

168

15

  
  1. * See definition in Methods section; PPV: positive predictive value; NPV negative predictive value
  2. a HCV-related severe events: ascites, varices bleeding, hepatic encephalopathy, hepatocellular carcinoma or HCV-related death