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Table 3 Variables associated with QFT-GIT reversion

From: Serial interferon-gamma release assays during treatment of active tuberculosis in young adults

 

Number (%)

Number with reversion (%)

Odds ratio (95%CI)

Pvalue

Cavity

    

   Present

18 (31.6)

6 (33.3)

1.00 (reference)

0.85

   Absent

39 (68.4)

12 (30.8)

1.13 (0.34-3.71)

 

Lesion extent

    

   > one lobe

28 (49.1)

8 (27.6)

1.00 (reference)

0.45

   one lobe

29 (50.9)

10 (35.7)

1.55 (0.50-4.77)

 

Pleural effusion

    

   Absent

43 (75.4)

11 (25.6)

1.00 (reference)

0.10

   Present

14 (24.6)

7 (50.0)

2.91 (0.83-10.17)

 

CRP

    

   < 3 mg/dl

41 (73.3)

10 (24.4)

1.00 (reference)

0.046

   ≥ 3 mg/dl

15 (26.8)

8 (53.3)

3.54 (1.03-12.24)

 

Body temperature*

    

   < 38.3°C

44 (76.8)

11 (25.6)

1.00 (reference)

0.056

   ≥ 38.3 °C

13 (23.2)

7 (53.8)

3.50 (0.97-12.67)

 

Baseline QFT-GIT

    

   decrease by 1 IU/ml

57 (100)

18 (31.6)

1.24 (1.03-1.49)

0.03

  1. All analysis was performed with exclusion of two participants with initial negative QFT.
  2. *Peak body temperature within 24 hours of initial hospital visit.
  3. QFT-GIT, QuantiFERON-TB gold in-tube assay; CRP, C-reactive protein.