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Figure 1 | BMC Infectious Diseases

Figure 1

From: CD36 deficiency attenuates experimental mycobacterial infection

Figure 1

Cd36 -/- mice have lower bacillary burden relative to Cd36 +/+ controls after challenge with M. bovis BCG. A. Intraperitoneal infection (day 0) with BCG (1.5×107 organisms) resulted in a rise in mycobacterial counts in the spleens of Cd36 +/+(wild type) mice to a maximum at day 14 with subsequent decline. The mycobacterial counts in Cd36 -/- mice (white box, dashed line) were lower overall (p < 0.001), and at specific time points (day 7, *p < 0.01; day 14, *p < 0.001). B and C. Differences between genotypes were less pronounced in the liver (B) and lung (C). Results are displayed as mean ± SEM, with 8 mice per group at each time point, representing two pooled independent experiments.

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