Table 2 Anti-PRP antibody response before dose 1 (pre) and one month post-dose 3 (post; ATP cohort for immunogenicity)
Time point | ≥0.15 μg/mL | ≥1.0 μg/mL | GMC | |||||
|---|---|---|---|---|---|---|---|---|
N | % | 95% CI | % | 95% CI | Value | 95% CI | ||
DTPw-HBV/Hib 2.5 [Kft] | Pre | 93 | 44.1 | 33.8-54.8 | 9.7 | 4.5-17.6 | 0.179 | 0.139-0.230 |
Post | 93 | 100 | 96.1-100 | 94.6 | 87.9-98.2 | 26.71 | 19.161-37.23 | |
DTPw-HBV/Hib | Pre | 89 | 42.7 | 32.3-53.6 | 10.1 | 4.7-18.3 | 0.177 | 0.137-0.227 |
Post | 89 | 100 | 95.9-100 | 100 | 95.9-100 | 40.75 | 32.301-51.40 | |
DTPw-HBV/Hib 2.5 | Pre | 84 | 42.9 | 32.1-54.1 | 8.3 | 3.4-16.4 | 0.167 | 0.131-0.212 |
Post | 85 | 98.8 | 93.6-100 | 94.1 | 86.8-98.1 | 19.58 | 14.019-27.36 | |