Diagnostic value of triggering receptor expressed on myeloid cells-1 and C-reactive protein for patients with lung infiltrates: an observational study

BMC Infectious Diseases

Table 2 Concentrations of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and of C-reactive protein (CRP) in the sera and expression of TREM-1 on neutrophils and on monocytes of 68 patients with pulmonary infiltrates.^§

	Survivors	Non-Survivors	p	Group A	Group B	p
	sTREM-1 (pg/ml, median-IQR)
Day1	28.13 (95.00)	189.61 (204.99)	0.028	102.09 (227.21)	< 15.10 (31.04)	< 0.0001
Day3	< 15.10 (39.45)	122.80 (231.05)	0.065	28.12 (263.74)	< 15.10 (21.10)	0.010
Day 7	< 15.10 (35.60)	52.30 (225.81)	0.055	12.96 (202.89)	< 15.10 (18.80)	0.022
	TREM-1 on neutrophils (MFI, mean ± SE)
Day1	3.55 ± 0.53	4.18 ± 1.07	NS*	4.67 ± 0.53	2.64 ± 0.25	0.001
Day3	2.26 ± 0.25	3.40 ± 1.10	NS	3.14 ± 0.37	1.57 ± 0.20	NS
Day 7	1.46 ± 0.31	2.34 ± 0.95	NS	1.20 ± 0.37	1.60 ± 0.43	NS
	TREM-1 on monocytes (MFI, mean ± SE)
Day1	3.24 ± 0.31	4.51 ± 0.91	NS	4.2 ± 0.42	2.64 ± 0.35	0.007
Day3	2.02 ± 0.33	3.42 ± 0.57	NS	1.50 ± 0.20	2.20 ± 0.43	0.001
Day 7	2.35 ± 0.25	4.25 ± 1.45	NS	1.76 ± 0.20	3.21 ± 0.43	0.003
	CRP (mg/dl, mean ± SE)
Day1	11.6 ± 1.5	16.6 ± 3.8	NS	18.03 ± 2	7.1 ± 1.5	< 0.001
Day3	9.4 ± 1.4	12.3 ± 2.7	NS	12.2 ± 2.0	7.1 ± 1.5	0.05
Day 7	6.4 ± 1.1	9.7 ± 3.5	NS	7.2 ± 1.5	6.2 ± 1.6	NS

*NS: non significant
^§Patients are divided into two groups; survivors and non-survivors; and into those with community-acquired pneumonia (group A) and into those with an infiltrate of non-infectious origin (group B).