| |
Survivors
|
Non-Survivors
|
p
|
Group A
|
Group B
|
p
|
|---|
| |
sTREM-1 (pg/ml, median-IQR)
|
|
Day1
|
28.13 (95.00)
|
189.61 (204.99)
|
0.028
|
102.09 (227.21)
|
< 15.10 (31.04)
|
< 0.0001
|
|
Day3
|
< 15.10 (39.45)
|
122.80 (231.05)
|
0.065
|
28.12 (263.74)
|
< 15.10 (21.10)
|
0.010
|
|
Day 7
|
< 15.10 (35.60)
|
52.30 (225.81)
|
0.055
|
12.96 (202.89)
|
< 15.10 (18.80)
|
0.022
|
| |
TREM-1 on neutrophils (MFI, mean ± SE)
|
|
Day1
|
3.55 ± 0.53
|
4.18 ± 1.07
|
NS*
|
4.67 ± 0.53
|
2.64 ± 0.25
|
0.001
|
|
Day3
|
2.26 ± 0.25
|
3.40 ± 1.10
|
NS
|
3.14 ± 0.37
|
1.57 ± 0.20
|
NS
|
|
Day 7
|
1.46 ± 0.31
|
2.34 ± 0.95
|
NS
|
1.20 ± 0.37
|
1.60 ± 0.43
|
NS
|
| |
TREM-1 on monocytes (MFI, mean ± SE)
|
|
Day1
|
3.24 ± 0.31
|
4.51 ± 0.91
|
NS
|
4.2 ± 0.42
|
2.64 ± 0.35
|
0.007
|
|
Day3
|
2.02 ± 0.33
|
3.42 ± 0.57
|
NS
|
1.50 ± 0.20
|
2.20 ± 0.43
|
0.001
|
|
Day 7
|
2.35 ± 0.25
|
4.25 ± 1.45
|
NS
|
1.76 ± 0.20
|
3.21 ± 0.43
|
0.003
|
| |
CRP (mg/dl, mean ± SE)
|
|
Day1
|
11.6 ± 1.5
|
16.6 ± 3.8
|
NS
|
18.03 ± 2
|
7.1 ± 1.5
|
< 0.001
|
|
Day3
|
9.4 ± 1.4
|
12.3 ± 2.7
|
NS
|
12.2 ± 2.0
|
7.1 ± 1.5
|
0.05
|
|
Day 7
|
6.4 ± 1.1
|
9.7 ± 3.5
|
NS
|
7.2 ± 1.5
|
6.2 ± 1.6
|
NS
|
- *NS: non significant
-
§Patients are divided into two groups; survivors and non-survivors; and into those with community-acquired pneumonia (group A) and into those with an infiltrate of non-infectious origin (group B).
