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Table 2 Concentrations of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and of C-reactive protein (CRP) in the sera and expression of TREM-1 on neutrophils and on monocytes of 68 patients with pulmonary infiltrates.§

From: Diagnostic value of triggering receptor expressed on myeloid cells-1 and C-reactive protein for patients with lung infiltrates: an observational study

 

Survivors

Non-Survivors

p

Group A

Group B

p

 

sTREM-1 (pg/ml, median-IQR)

Day1

28.13 (95.00)

189.61 (204.99)

0.028

102.09 (227.21)

< 15.10 (31.04)

< 0.0001

Day3

< 15.10 (39.45)

122.80 (231.05)

0.065

28.12 (263.74)

< 15.10 (21.10)

0.010

Day 7

< 15.10 (35.60)

52.30 (225.81)

0.055

12.96 (202.89)

< 15.10 (18.80)

0.022

 

TREM-1 on neutrophils (MFI, mean ± SE)

Day1

3.55 ± 0.53

4.18 ± 1.07

NS*

4.67 ± 0.53

2.64 ± 0.25

0.001

Day3

2.26 ± 0.25

3.40 ± 1.10

NS

3.14 ± 0.37

1.57 ± 0.20

NS

Day 7

1.46 ± 0.31

2.34 ± 0.95

NS

1.20 ± 0.37

1.60 ± 0.43

NS

 

TREM-1 on monocytes (MFI, mean ± SE)

Day1

3.24 ± 0.31

4.51 ± 0.91

NS

4.2 ± 0.42

2.64 ± 0.35

0.007

Day3

2.02 ± 0.33

3.42 ± 0.57

NS

1.50 ± 0.20

2.20 ± 0.43

0.001

Day 7

2.35 ± 0.25

4.25 ± 1.45

NS

1.76 ± 0.20

3.21 ± 0.43

0.003

 

CRP (mg/dl, mean ± SE)

Day1

11.6 ± 1.5

16.6 ± 3.8

NS

18.03 ± 2

7.1 ± 1.5

< 0.001

Day3

9.4 ± 1.4

12.3 ± 2.7

NS

12.2 ± 2.0

7.1 ± 1.5

0.05

Day 7

6.4 ± 1.1

9.7 ± 3.5

NS

7.2 ± 1.5

6.2 ± 1.6

NS

  1. *NS: non significant
  2. §Patients are divided into two groups; survivors and non-survivors; and into those with community-acquired pneumonia (group A) and into those with an infiltrate of non-infectious origin (group B).