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Table 3 Efficacy of multiplex-HPV PCR, HC2, and Chip, based on direct sequencing.

From: Detection of sexually transmitted infection and human papillomavirus in negative cytology by multiplex-PCR

 

True Positive

True Negative

False Positive

False Negative

HPV-all- Negative

PCR

48

175

5

7

235

HC2

45

173

6

9

233

Chip

47

176

4

8

235

 

Sensitivity

Sensitivity-l

Sensitivity-u

Specificity

Specificity-l

Specificity-u

AUC

PCR

87.2727

78.4646

96.0808

97.2222

94.8214

99.6230

0.922

HC2

83.3333

73.3932

93.2735

96.6480

94.0113

99.2848

0.900

Chip

85.4545

76.1369

94.7722

97.7778

95.6243

99.9312

0.916

 

PPV

PPV-l

PPV-u

NPV

NPV-l

NPV-u

Accuracy

PCR

90.5660

82.6965

98.4356

96.1538

93.3599

98.9478

94.8936

HC2

88.2353

79.3926

97.0779

95.0549

91.9051

98.2048

93.5622

Chip

92.1569

84.7782

99.5356

95.6522

92.7055

98.5988

94.8936

  1. -l: lower limit of 95% confidence interval, -u: upper limit of 95% confidence interval.
  2. AUC: area under the curve
  3. PPV: positive predictive value,
  4. NPV: negative predictive value