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Table 4 Levels of HMGB1, LBP, IL-6 and CRP in children with and without bacteraemia.

From: High-mobility group box-1 protein, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in children with community acquired infections and bacteraemia: a prospective study

Biomarker Infection without bacteraemia (n = 74) Infection with bacteraemia
(n = 30)
p-value1
HMGB12 (ng/ml) 3.0 (1 -- 7.4)6 3.2 (1.2 -- 10.9) ns7
LBP3(μg/ml) 23.7 (16.6 -- 38.5) 63.4 (28.3 -- 86) < 0.001
IL-64 (pg/ml) 21.2 (10.5 -- 46.6) 178.1 (62.3 -- 464.8) < 0.001
CRP5 (mg/l) 54.5 (16.1 -- 91.1) 212.8 (100.7 -- 247.4) < 0.001
  1. 1Mann - Whitney test.;2high mobility box-1 protein; 3lipopolysaccharide-binding proteine; 4interleukine-6; 5C-reactive protein; 6median and interquartile range (IQR). 7not significant.