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Table 2 Detection rate of different techniques and comparison of incremental yield over direct microscopy alone

From: Direct microscopy versus sputum cytology analysis and bleach sedimentation for diagnosis of tuberculosis: a prospective diagnostic study

 

Case definition of one smear

Case definition of two smears

 

N detected (% of all patients)

Incremental yield over D alone: N (%; 95% CI)

N detected (% of all patients)

Incremental yield over D alone: N (%; 95% CI)

D

121 (43.2%)*

-

118 (42.1%)

-

D+SCA

122 (43.6%)

1 (0.8%; 0-4.5)

118 (42.1%)

0

B

134 (47.9%)†

14 (11.6%; 6.5-18.6)

123 (43.9%)

5 (4.2%; 1.4-9.6)

B+SCA

135 (48.6%)‡

15(12.4%; 7.1-19.6)

125 (44.6%)

7 (5.9%; 2.4-11.8)

  1. D = direct microscopy. SCA = sputum cytology analysis. B = bleach sedimentation. *One patient was positive on direct microscopy and negative on sediment microscopy, resulting in a total of 121 patients diagnosed by direct microscopy, of which 120 were positive on sediment microscopy. †One patient positive on direct but negative on sediment in three samples (without SCA). ‡One patient positive on sediment but not on direct microscopy after SCA.