Table 3 Clinical status and viral mutations in patients of HBeAg negative and positive.

Gender (Male/Female)

21/4

92/38

113/42

0.13^b

Age (years, Mean ± SD)

42 ± 14

38 ± 13

39 ± 14

0.165*

Clinical status (ALD/PLD)

16/9

50/81

66/90

0.015 ^b

HBV DNA titer (lg, Mean ± SD)

6 ± 1

7 ± 2

7 ± 1

0.127*

ALT (U/L, Mean ± SD)

258 ± 466

178 ± 230

191 ± 279

0.199*

AST (U/L, Mean ± SD)

203 ± 328

104 ± 111

119 ± 165

0.008*

nt 1753 (m/wt)

5/20

18/113

23/133

0.296^b

nt 1762 (m/wt)

19/6

85/46

104/52

0.2^b

nt 1764 (m/wt)

19/6

89/42

108/48

0.292^b

nt 1776 (m/wt)

5/20

3/128

8/148

0.003 ^b

nt 1846 (m/wt)

6/19

10/121

16/140

0.024 ^b

nt 1896 (m/wt)

12/13

28/103

40/116

0.007 ^b

nt 1899 (m/wt)

2/23

2/129

4/152

0.121^b

Mutation≥3 (Y/N)

15/10

47/84

62/94

0.022 ^b