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Table 2 Comparison of characteristics of patients that are or are not part of a transmission cluster.

From: Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections

  cluster cluster   Multivariate Bin. Log. Regression
  Count Count p-value ODDS ratio 95% CI p-value
# Patienten (n = 506) 169 (33.4%) 337 (66.6%)     
Subtype B 143/169 (84.6%) 159/337 (47.2%) < 0.001    -
Homosexual transmission 125/150 (83.3%) 117/258 (45.3%) < 0.001 3.1 1.8 - 5.4 < 0.001
HBV + 56/167 (33.5%) 132/324 (40.7%) 0.12    -
HCV + 14/167 (8.4%) 20/325 (6.2%) 0.356    
Syphilis + 68/169 (40.2%) 72/331 (21.8%) < 0.001    -
Chlamydia + 61/151 (40.4%) 66/234 (28.2%) 0.013    -
Gender (male) 154/169 (91.1%) 219/337 (64.4%) < 0.001    -
Caucasian origin 158/166 (95.2%) 195/335 (58.2%) < 0.001 14.5 4.2 - 49.9 < 0.001
DRM 12/169 (7.1%) 21/337 (6.2%) 0,709    
PHI 34/162 (21.0%) 38/302 (12.6%) 0.017    -
  Median (IQR) Median (IQR) p-value    
CD4 + T cells (cells/μl) 419.5 (311-580) 351 (192-550) 0.002    -
Age (years) 36 (31-42) 38 (32-45) 0.067 0.9 0.92 - 0.97 < 0.001
  1. Values are given as counts per number of patients of which data was available. For the multivariate analysis, odds ratios are given with regard to being a member of a cluster ( cluster). The p-value for the Hosmer-Lemeshow test for the multivariate model is 0.876.
  2. HBV, Hepatitis B Virus; HCV, Hepatitis C Virus; DRM, Drug Resistant Mutations; PHI, Primary HIV Infection; IQR, interquartile range; CI, confidence interval.