Table 4 Comparison of patients treated with and without corticosteroids
No corticosteroids (n = 103) | Corticosteroids (n = 52) | Univariate analysis OR (95%CI) | Multivariate analysis OR (95%CI) | |
|---|---|---|---|---|
Comorbidity | ||||
Cardiovascular diseases | 35 | 10 | 0.463 (0.208 - 1.031) | |
Chronic lung diseases | 20 | 2 | 0.116 (0.037 - 0.740) | |
Symptoms at disease onset | ||||
Dyspnea | 40 | 33 | 2.736 (1.373 - 5.452) | |
Hemoptysis | 9 | 10 | 2.487 (0.942 - 6.568) | |
On hospital admission | ||||
Dyspnea | 42 | 40 | 4.841 (2.275 - 10.304) | |
Pneumonia on CXR | 81 | 48 | 3.259 (1.060 - 10.025) | |
Laboratory tests on admission | ||||
CPK | 260 ± 447 | 577 ± 795 | 1.001 (1.000 - 1.002) | |
CK-MB | 20 ± 30 | 32 ± 33 | 1.014 (0.997 - 1.032) | |
LDH, per 100 U/L increase | 305 ± 229 | 658 ± 572 | 1.508 (1.219 - 1.866) | 1.401 (1.107 - 1.773) |
Complications | ||||
Acute respiratory failure | 24 (23.3%) | 38 (73.1%) | 8.935 (4.160 - 19.187) | 8.738 (2.504 - 30.489) |
Septic shock | 5 (4.9%) | 13 (25.0%) | 6.533 (2.183 - 19.551) | |
Acute renal failure | 5 (4.9%) | 10 (19.2%) | 4.667 (1.503 - 14.486) | |
Altered mental status | 9 (8.7%) | 11 (21.2%) | 2.842 (1.093 - 7.390) | |
Bloodstream infection | 0 | 3 | 1.061 (0.992 - 1.135) | |
Other infections | 1 | 4 | 8.500 (0.925 - 78.106) | |
Supportive treatment | ||||
Vasopresssors | 9 | 19 | 6.013 (2.478 - 14.596) | |
Neuromuscular blockade | 1 | 7 | 15.867 (1.896 - 132.776) | |
Noninvasive ventilation | 11 | 21 | 5.666 (2.467 - 13.063) | |
Invasive ventilation | 16 | 27 | 5.873 (2.742 - 12.578) |