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Table 2 Equilibrium fraction of infected patients with different interventions

From: Antibiotic control of antibiotic resistance in hospitals: a simulation study

Intervention (changes in hospital protocol)

Percent of Infected Patients at Equilibrium

Standard Parameters*

52.8

Reduce transmission (βS0) by a factor of two

37.3

Reduce the term of stay of uncolonized patients (1/CU) by a factor of two

60.8

Reduce the term of stay of infected patients (1/CS0) by a factor of two

44.7

Reduce the input of colonized patients entering the hospital (eS) by a factor of two

43.3

Treat 50% of colonized patients with an antibiotic (f = 0.5) - no resistance

21.4

  1. * Standard parameters: βS0 = 2 × 10-3, CU = 0.10, CS0 = 0.05, eS = 0.40, eU = 0.20
  2. x = 0.10 (clearance rate in the absence of treatment - 10 days), v = 0.3333 (clearance rate with treatment - 3 days), βS1 = 2 × 10-3 (transmission rate of treated patients with susceptible bacteria). Total and sustained number of patients N = 100. Note: A number of these parameters are different than those used in simulations presented in the body of this report.