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Table 1 Parameters and their default values.

From: Antibiotic control of antibiotic resistance in hospitals: a simulation study

Symbol

Description

Value in Simulations

eS

Proportion colonized with sensitive bacteria among patients entering the hospital

0.40

eR

Proportion colonized with resistant bacteria among patients entering the hospital

0.0 - 0.2

β S0

Transmission rate of sensitive bacteria from an untreated patient

0.007

β S1

Transmission rate of sensitive bacteria from a patient treated with drug 1

0.007

β S2

Transmission rate of sensitive bacteria from a patient treated with drug 2

0.007

β R0

Transmission rate of resistant bacteria from an untreated patient

0.007

β R1

Transmission rate of resistant bacteria from a patient treated with drug 1

0.007

β R2

Transmission rate of resistant bacteria from a patient treated with drug 2

0.007

f S

Rate of initiating treatment with drug 1 for a patient in

varies

f R

Rate of initiating treatment with drug 1 for a patient in

varies

sw S

Rate of switching to drug 2 for a patient in

varies

sw R

Rate of switching to drug 2 for a patient in

varies

x

Rate of clearance for patients who are not treated or are treated with an ineffective drug

0.10

v

Additional rate of clearance for patients who are treated with an effective drug

0.50

c U

Rate of exiting hospital for patients in U.

0.20

C S

Rate of exiting hospital for patients in S.

0.10

C R

Rate of exiting hospital for patients in R.

0.10

  1. All the rates are daily rates.