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Table 3 Sensitivity of AFB and multiplex-PCR as diagnostic tools in detecting multibacillary leprosy cases among different categories of multibacillary patients

From: Multiplex PCR technique could be an alternative approach for early detection of leprosy among close contacts - a pilot study from India

BL n = 53
Clinical status of the disease Cases confirmed by AFB In SSS(Slit skin smear) Cases confirmed by Multiplex-PCR Percent of positivity by AFB test Percent of positivity of M-PCR test
  BI No of case    
Patients without treatment (New Cases)(n = 44) 2 23 23 100% 100%
  3 11 11   
  4 10 10   
Patients on treatment not more than 2 months (n = 5) 0 4 2(50%) 25% 60%
  2 1 1   
  3 0 0   
  4 0 0   
Patients released from treatment (RFT)(a)/later developed a new active lesion/relapsed cases(b) (n = 4) 0 2a, 2(0%) 50% 50%
  2 1a 1a   
  3 1b 1b   
Total n = 53     71.6% (38/53) 88.67% (47/53)
LL n = 152
Clinical status of the disease Cases confirmed by AFB In SSS(Slit skin smear) Cases confirmed by Multiplex-PCR Percent of positivity by AFB test Percent of positivity of M-PCR test
  BI No of case    
Patients without treatment (New Cases)(n = 115) 2 8 8 100% 100%
  3 35 35   
  4 37 37   
  5 31 31   
  6 4 4   
Patients on treatment not more than 2 months (n = 12) 0 4 1(25%) 66.66% 75%
  2 3 3   
  3 2 2   
  4 3 3   
  5 0 0   
  6 0 0   
Patients released from treatment (RFT)(a)/later developed a new active lesion/relapsed cases(b) (n = 25) 0 14a,1b 2(13.33%) 40% 48%
  2 1a,2b 3   
  3 2b 2   
  4 2a,1b 3   
  5 1a 1   
  6 1a 1   
Total n = 152     83.4% (133/152) 89.2% (136/152)