| HZ | PHN | HZ plus PHN |  |  |
---|---|---|---|---|---|
Number of expected cases in Italian population per year | 129,435 | 12,228 (PHN1 only*) | Â | Â | Â |
 | Mean € | Total €m | Mean € | Total €m | Total €m |
Direct outpatient costs | 123 | 15.9 | 446 | 5.3 | 21.2 |
Direct hospital costs | 43 | 5.6 | 114 | 1.4 | 7.0 |
Total direct costs | 166 | 21.5 | 560 | 6.7 | 28.2 |
Indirect costs | 556 | 12.2 | 795 | 0.8 | 13.0 |
Total costs | Â | 33.7 | Â | 7.5 | 41.2 |