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Table 3 Changes in TB incidence rate during antiretroviral therapy among 583 patients initiating treatment.

From: The tuberculosis challenge in a rural South African HIV programme

  Initial 3 months (n = 583 individuals)   After 3 months (n = 559 individuals)  
Variable Unadjusted Hazard Ratio (95% CI) Adjusted Hazard Ratio (95% CI) Unadjusted Hazard Ratio (95% CI) Adjusted Hazard Ratio (95% CI)
Age (years) 0.99 (0.95-1.04) 0.87 (0.79-0.96) 0.98 (0.95-1.10) N/S
Sex;     
   Female REF   REF  
   Male 4.17 (1.83-.54) 9.55 (2.35-38.78) 0.59 (0.30-1.16) 0.55 (0.27-1.10)
Log 10 HIV RNA 1.85 (0.86-3.97) 2.69 (1.11-6.51) 0.83 (0.59-1.13) N/S
Transfer in 0.99 (0.13-7.30) N/S 0.38 (0.05-2.78) N/S
Log 10 CD4 1.35 (0.78-2.40) 2.02 (0.58-4.76) 0.83 (0.65-1.07) 0.87(0.67-1.13)
Prior TB;     
No REF   REF  
Yes 1.42 (0.63-3.20) 1.16 (0.33-4.03) 1.77 (1.04-2.98) 1.32 (0.73-2.38)
WHO stage     
1 or 2 REF   REF  
3 or 4 2.33 (0.92-5.92) N/S 2.11 (1.15-3.87) 1.94 (0.99-3.38)
Unknown 0.40 (0.05-3.32) N/S 1.27 (0.52-3.12) 1.43 (0.58-3.56)