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Table 4 Histopathological observations in aged, immunocompetent mice experimentally inoculated with three different Bartonella tamiae isolates [NAF = No Abnormal Finding]

From: Human isolates of Bartonella tamiaeinduce pathology in experimentally inoculated immunocompetent mice

Bartonella tamiaeisolates
Week post-inoculation Th239 Th307 Th339
3 Skin NAF Dermatitis, deep, not oriented Necrotizing dermatitis
  Spleen NAF NAF NAF
  Liver NAF NAF NAF
4 Skin NAF NAF Necrotizing dermatitis
  Spleen NAF NAF NAF
  Liver Granulomatous hepatitis w/necrosis NAF Diffuse inflammatory response in sinusoids
  Kidney Granulomatous nephritis NAF NAF
5 Spleen NAF   Hemosiderosis in the cortex
  Liver NAF NAF NAF
  Kidney Perivascular granulomatous nephritis Granulomas in the cortex and medulla NAF
  Lymph nodes Pyogranulomatous lymphadenitis NAF NAF
  Heart Myocarditis, granulomas right & left atria, infiltrates No sample Myocarditis, granulomas right & left atria, infiltrates
6 Skin No sample Deep dermatitis No sample
  Spleen Pyogranulomatous nodules in the red and white pulp NAF NAF
  Liver Hepatitis, granulomas w/necrosis NAF Perivascular granulomas, hepatocellular necrosis
  Kidney NAF Large perivascular granulomas NAF
  Lymph nodes Lymphadenitis NAF Lymphadenitis, cortical granulomas, necrotizing vasculitis