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Table 5 Risk factors related to prior antimicrobial therapya

From: Risk factors for multi-drug resistant Acinetobacter baumanniibacteremia in patients with colonization in the intensive care unit

 

Non-Bacteremic

(n = 92)

Bacteremic

(n = 108)

Odds

Ratio

95% CI

P-value

Non-Bacteremic

(days)

Bacteremic

(days)

P-value

Number (percentage) of prior exposure antibiotics/duration of exposure, days

2.7 ± 1.1

3.8 ± 1.4

2.09

1.60 - 2.74

< 0.001

19.2 ± 21.3

13.2 ± 12.9

0.005

   Aminopenicillin

2 (2.2)

3 (2.8)

1.29

0.21 - 7.87

0.79

9.5 ± 2.1

6.7 ± 6.4

0.601

   Cephalosporin

34 (37.0)

34 (31.5)

0.78

0.44 - 1.41

0.416

11.2 ± 9.1

7.9 ± 6.8

0.09

   Quinolone

37 (40.2)

50 (55.6)

1.86

1.06 - 3.27

0.031

11.6 ± 6.2

7.8 ± 3.4

0.002

   Antipseudomonal penicillin

34 (37.0)

44 (40.7)

1.17

0.66 - 2.08

0.585

10.6 ± 5.1

6.3 ± 2.9

< 0.001

   Carbapenem

45 (48.9)

83 (76.9)

3.47

1.89 - 6.36

< 0.001

14.1 ± 14.9

9.2 ± 6.0

0.003

   Glycopeptide

52 (56.5)

85 (78.7)

2.84

1.53 - 5.28

0.001

12.6 ± 7.6

9.3 ± 7.8

0.018

   Aminoglycoside

10 (10.9)

30 (27.8)

3.15

1.45 - 6.88

0.004

8 ± 4.1

5.6 ± 3.8

0.099

   Anti-anaerobe

24 (26.1)

38 (35.2)

1.54

0.84 - 2.83

0.167

9.0 ± 4.6

6.3 ± 4.1

0.017

   Macrolide

2 (2.2)

5 (4.6)

2.18

0.41 - 11.54

0.357

5.5 ± 3.5

4.4 ± 2.6

0.660

  1. a Data are presented as numbers (percentages) unless otherwise indicated. Plus-minus values are means ± standard deviation
  2. CI confidential interval
  3. SD standard deviation