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Table 2 Risk factors related to clinical characteristics a

From: Risk factors for multi-drug resistant Acinetobacter baumanniibacteremia in patients with colonization in the intensive care unit

Parameters Non-Bacteremic
(n = 92)
Bacteremic
(n = 108)
Odds
Ratio
95% CI P-value
Immunosuppressive status b 45 (48.9) 89 (82.4) 4.89 2.57 - 9.29 < 0.001
Neutropenia c 2 (2.2) 25 (23.1) 13.55 3.11 - 59.0 0.001
Prior history of      
   ICU admission 2 (2.2) 6 (5.6) 2.65 0.52 - 13.45 0.240
   Hospitalization 24 (26.1) 41 (38.0) 1.73 0.95 - 3.18 0.075
APACHE II score at the time of      
   ICU admission (point) 21.6 ± 8.2 24.0 ± 7.9 1.04 1.00 - 1.08 0.035
   Colonization (point) 17.0 (12.0 - 20.0) 22.0 (17.0 - 28.0) 1.12 1.07 - 1.17 <0.001
Duration (days)      
   Of hospitalization 31.0 (20.0 - 65.3) 32.0 (20.0 - 5.0) 0.99 0.99 - 1.00 0.333
   Of ICU hospitalization 19.2 ± 21.3 22.8 ± 20.4 1.01 0.99 - 1.02 0.234
   From ICU admission to colonization 7.1 ± 7.7 7.2 ± 5.9 1.00 0.96 - 1.01 0.923
   Of exposure to riskd 6.0 (3.0 - 13.8) 3.0 (1.0 - 6.0) 0.96 0.94 - 0.99 <0.001
Mechanical ventilator care 87 (94.6) 105 (97.2) 2.01 0.47 - 8.66 0.348
   Maintenance of MVe 15 (17.2) 91 (86.7) 31.2 14.14 - 68.83 < 0.001
   Duration of MV (day) 9.0 (5.0 - 16.0) 21.5 (12.3 - 47.0) 1.04 1.01 - 1.08 0.001
Shock at the time of      
   ICU admission 66 (71.7) 80 (74.1) 1.13 0.60 - 2.10 0.711
   Colonization 28 (30.4) 65 (60.2) 3.46 1.92 - 6.22 < 0.001
Acute renal failure at the time of      
   ICU admission 22 (23.9) 31 (28.7) 1.28 0.68 - 2.42 0.445
   Colonization 20 (21.7) 41 (38.0) 2.20 1.17 - 4.14 0.014
  1. a Data are presented as numbers (percentages for categorical variables or interquartile range for continuous variables) unless otherwise indicated. Plus-minus values are means ± standard deviation
  2. b Immunosupression was defined as a history of any of the following: corticosteroid therapy for 15 days (at least 10 mg/day of prednisone or an equivalent drug), seropositivity for human immunodeficiency virus, solid organ transplantation, bone marrow transplantation, radiation therapy or chemotherapy for an underlying malignancy during the 6 months prior to hospital admission, and acquired immune deficiency disorder (hypogammaglobulinemia, combined variable immunodeficiency).
  3. c Neutropenia is defined as absolute neutrophil count measured in cells per microliter of blood less than 1,500
  4. d Time from colonization to the date of discharge from the intensive care unit for non-bacteremic patients or to the date a positive-culture was obtained for bacteremic patients
  5. e Number of patients/total number of patients with mechanical ventilation (percentages)
  6. ICU intensive care unit
  7. APACHE Acute Physiological Assessment and Chronic Health Evaluation
  8. MV mechanical ventilation
  9. CI confidential interval