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Table 5 Multivariate multinomial logistic regressions for the changes of liver image patterns for Ségou area (n = 427)

From: The impact of single versus mixed schistosome species infections on liver, spleen and bladder morbidity within Malian children pre- and post-praziquantel treatment

Estimates from multinomial model with dependent variable indicating the change of liver image patterns during the 2 time points of the study

(Adjusted ORs for gender and age, 95% CIs & p-values)

 

Dependent variable: the risk of having pathology at both time points

Dependent variable: the risk of having no pathology at baseline and having pathology at final point of the study

Dependent variable: the risk of having pathology at baseline but cured at final point of the study

Risk factors-Independent variables at baseline(Reference category)

   

Type of schistosomiasis infection related variables at baseline

   

Infected with S. haematobium (Not infected with S. haematobium)

0.353 (0.080 to 1.560) p = 0.1691

2.339 (0.525 to 10.423) p = 0.2651

0.245 (0.110 to 0.544) p < 0.0011

Infected with S. mansoni (Not infected with S. mansoni)

34.591 (4.315 to 277.268) p < 0.0011

7.139 (3.513 to 14.506) p < 0.0011

3.081 (1.514 to 6.267) p = 0.0021

Estimates from model with dependent variable indicating the change of portal hypertension from ultrasound during the 2 time points of the study

Type of schistosomiasis infection related variables at baseline

   

Infected with S. haematobium (Not infected with S. haematobium)

0.157 (0.036 to 0.695) p = 0.0151

1.541 (0.346 to 6.865) p = 0.5711

0.612 (0.230 to 1.631) p = 0.3271

Infected with S. mansoni (Not infected with S. mansoni)

2.792 (0.611 to 12.753) p = 0.1851

0.188 (0.043 to 0.813) p = 0.0251

3.076 (1.460 to 6.482) p = 0.0031

Estimates from model with dependent variable indicating the change of splenomegaly from clinical examination and MCL>2 during the 2 time points of the study

Type of schistosomiasis infection related variables at baseline

   

Infected with S. haematobium (Not infected with S. haematobium)

0.356 (0.129 to 0.983) p = 0.0461

1.105 (0.136 to 9.009) p = 0.9261

0.482 (0.253 to 0.919) p = 0.0271

Infected with S. mansoni (Not infected with S. mansoni)

2.946 (1.267 to 6.848) p = 0.0121

0.915 (0.235 to 3.562) p = 0.8991

1.479 (0.900 to 2.432) p = 0.1231

Estimates from model with dependent variable indicating the change of splenomegaly from clinical examination and MAL>2 during the 2 time points of the study

Type of schistosomiasis infection related variables at baseline

   

Infected with S. haematobium (Not infected with S. haematobium)

0.505 (0.155 to 1.647) p = 0.2571

1.028 (0.125 to 8.474) p = 0.9791

0.487 (0.256 to 0.929) p = 0.0291

Infected with S. mansoni (Not infected with S. mansoni)

4.353 (1.681 to 11.272) p = 0.0021

0.953 (0.238 to 3.810) p = 0.9461

1.140 (0.681 to 1.908) p = 0.6191

  1. Note: The comparison group for the dependent variable is 'no pathology at both time points'
  2. ORs, Odds Ratios; 95% CIs, 95% Confidence Intervals