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Table 3 Deaths rates and hazard ratios (HR) with 95% confidence intervals (CI) for the independent relationship between pneumococcal vaccination (vs. no pneumococcal vaccination), and influenza vaccination (vs. no influenza vaccination) and death among asplenic subjects

From: Pneumococcal and influenza immunization in asplenic persons: a retrospective population-based cohort study 1990-2002

Diagnosis category Pneumococcal vaccination Influenza vaccination
  Death rates (per 1000 person-years) HR, 95% CI* Death rates (per 1000 person-years) HR, 95% CI*
  Pneumococcal vaccination No pneumococcal vaccination   Influenza vaccination No influenza vaccination  
ITP 16.80 32.35 0.91, 0.33-2.54 16.00 52.79 0.36, 0.18-0.74
Hodgkins disease 0.00 53.50 Indeterminate 23.97 74.21 indeterminate
Non-Hodgkins lymphoma 45.77 59.02 1.00, 0.32-3.09 42.59 75.37 0.45, 0.19-1.08
Hemolytic anemia 25.10 38.78 1.89, 0.31-11.44 17.65 84.98 0.10, 0.12-0.55
Hypersplenism 15.77 18.16 3.21, 0.32-32.13 10.16 27.37 0.17, 0.02-1.38
Splenectomy, no pre-existing hematologic diagnosis 41.81 57.21 1.11, 0.61-2.01 39.58 68.43 0.52, 0.34-0.78
Overall (all asplenic patients) 28.44 45.78 1.07, 0.70-1.65 27.00 61.67 0.46, 0.33-0.62
  1. ITP = immune thrombocytopenic purpura
  2. * Adjusted for age at diagnosis and gender.
  3. † Adjusted for age at diagnosis, gender and diagnostic category.