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Table 3 Deaths rates and hazard ratios (HR) with 95% confidence intervals (CI) for the independent relationship between pneumococcal vaccination (vs. no pneumococcal vaccination), and influenza vaccination (vs. no influenza vaccination) and death among asplenic subjects

From: Pneumococcal and influenza immunization in asplenic persons: a retrospective population-based cohort study 1990-2002

Diagnosis category

Pneumococcal vaccination

Influenza vaccination

 

Death rates (per 1000 person-years)

HR, 95% CI*

Death rates (per 1000 person-years)

HR, 95% CI*

 

Pneumococcal vaccination

No pneumococcal vaccination

 

Influenza vaccination

No influenza vaccination

 

ITP

16.80

32.35

0.91, 0.33-2.54

16.00

52.79

0.36, 0.18-0.74

Hodgkins disease

0.00

53.50

Indeterminate

23.97

74.21

indeterminate

Non-Hodgkins lymphoma

45.77

59.02

1.00, 0.32-3.09

42.59

75.37

0.45, 0.19-1.08

Hemolytic anemia

25.10

38.78

1.89, 0.31-11.44

17.65

84.98

0.10, 0.12-0.55

Hypersplenism

15.77

18.16

3.21, 0.32-32.13

10.16

27.37

0.17, 0.02-1.38

Splenectomy, no pre-existing hematologic diagnosis

41.81

57.21

1.11, 0.61-2.01

39.58

68.43

0.52, 0.34-0.78

Overall (all asplenic patients) †

28.44

45.78

1.07, 0.70-1.65

27.00

61.67

0.46, 0.33-0.62

  1. ITP = immune thrombocytopenic purpura
  2. * Adjusted for age at diagnosis and gender.
  3. † Adjusted for age at diagnosis, gender and diagnostic category.