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Table 2 Hazards ratios (HR) and 95% confidence intervals (CI) for the relationship between splenectomy (Vs. no splenectomy) and death among subjects with a hematologic condition*

From: Pneumococcal and influenza immunization in asplenic persons: a retrospective population-based cohort study 1990-2002

Diagnosis category

Death rates (per 1000 person-years)

HR, 95% CI†

 

Splenectomy

No splenectomy

 

ITP

36.28

26.21

1.57, 1.08-2.29

Hodgkins disease

57.98

26.61

6.47, 2.83-14.81

Non-Hodgkins lymphoma

75.30

56.29

1.58, 1.05-2.39

Hemolytic anemia

45.18

21.80

3.40, 1.76-6.57

Hypersplenism

19.68

5.05

1.16, 0.59-2.26

Overall (all patients with a hematologic condition) ‡

39.65

15.34

1.75, 1.37-2.24

  1. ITP = immune thrombocytopenic purpura
  2. * Rates and HR calculated using the time-dependent covariate approach where follow-up time for subjects with splenectomy is divided into pre- and post-splenectomy
  3. † Adjusted for age at diagnosis and gender.
  4. ‡ Adjusted for age at diagnosis, gender and diagnostic category.
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BMC Infectious Diseases

ISSN: 1471-2334

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