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Table 2 Hazards ratios (HR) and 95% confidence intervals (CI) for the relationship between splenectomy (Vs. no splenectomy) and death among subjects with a hematologic condition*

From: Pneumococcal and influenza immunization in asplenic persons: a retrospective population-based cohort study 1990-2002

Diagnosis category Death rates (per 1000 person-years) HR, 95% CI
  Splenectomy No splenectomy  
ITP 36.28 26.21 1.57, 1.08-2.29
Hodgkins disease 57.98 26.61 6.47, 2.83-14.81
Non-Hodgkins lymphoma 75.30 56.29 1.58, 1.05-2.39
Hemolytic anemia 45.18 21.80 3.40, 1.76-6.57
Hypersplenism 19.68 5.05 1.16, 0.59-2.26
Overall (all patients with a hematologic condition) 39.65 15.34 1.75, 1.37-2.24
  1. ITP = immune thrombocytopenic purpura
  2. * Rates and HR calculated using the time-dependent covariate approach where follow-up time for subjects with splenectomy is divided into pre- and post-splenectomy
  3. † Adjusted for age at diagnosis and gender.
  4. ‡ Adjusted for age at diagnosis, gender and diagnostic category.