Table 6 Microbiologic eradication at the isolate level: selected baseline isolates at test-of-cure visit (ME population)
Tigecycline (N = 52) | Imipenem/cilastatin (N = 48) | |||||
|---|---|---|---|---|---|---|
Baseline Isolate | N | E | ER (%) | N | E | ER (%) |
Total | 83 | 69 | 83.1 | 75 | 74 | 98.7 |
Gram negative aerobic bacteria | 56 | 48 | 85.7 | 59 | 58 | 98.3 |
E. coli | 42 | 37 | 88.1 | 44 | 43 | 97.7 |
Other Enterobacteriaceae | 8 | 6 | 75.0 | 9 | 9 | 100 |
Non-fermentative Gram-negative bacilli | 6 | 5 | 83.3 | 6 | 6 | 100 |
Gram positive aerobic bacteria | 15 | 12 | 80.0 | 8 | 8 | 100 |
Enterococcus spp. | 10 | 8 | 80.0 | 5 | 5 | 100 |
Streptococcus spp. | 5 | 4 | 80.0 | 2 | 2 | 100 |
Staphylococcus spp. | 0 | 0 | 0 | 1 | 1 | 100 |
Anaerobe | 12 | 9 | 75.0 | 8 | 8 | 100 |
Bacterioides spp. | 7 | 5 | 71.4 | 6 | 6 | 100 |
Other anaerobe | 5 | 4 | 80.0 | 2 | 2 | 100 |