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Table 6 Microbiologic eradication at the isolate level: selected baseline isolates at test-of-cure visit (ME population)

From: Efficacy and safety of tigecycline monotherapy vs. imipenem/cilastatin in Chinese patients with complicated intra-abdominal infections: a randomized controlled trial

  Tigecycline (N = 52) Imipenem/cilastatin (N = 48)
Baseline Isolate N E ER (%) N E ER (%)
Total 83 69 83.1 75 74 98.7
Gram negative aerobic bacteria 56 48 85.7 59 58 98.3
   E. coli 42 37 88.1 44 43 97.7
   Other Enterobacteriaceae 8 6 75.0 9 9 100
   Non-fermentative Gram-negative bacilli 6 5 83.3 6 6 100
Gram positive aerobic bacteria 15 12 80.0 8 8 100
   Enterococcus spp. 10 8 80.0 5 5 100
   Streptococcus spp. 5 4 80.0 2 2 100
   Staphylococcus spp. 0 0 0 1 1 100
Anaerobe 12 9 75.0 8 8 100
   Bacterioides spp. 7 5 71.4 6 6 100
   Other anaerobe 5 4 80.0 2 2 100
  1. E = eradication (presumed), and ER = eradication rate.