Figure 1

Symptoms and neurological signs compared to absolute cortisol increment in Lyme neuroborreliosis patients post treatment. Numbers of symptoms and neurological signs at follow up 2.3 to 3.7 years post treatment (x-axis) and absolute cortisol increment (ACI) after 0.25 mg Synacthen^® injection (y-axis) in Lyme neuroborreliosis patients (n = 20). Pearson correlation coefficient r = 0.68; p = 0.001. The post treatment severity (PTS) score was calculated by adding the number of symptoms and pathological neurological signs strictly related to the Lyme neuroborreliosis infection for each patient. The dotted line at score = 4 represents a chosen cut off. Patients with a score above 4 were considered having more pronounced complaints (LNB⁺ n = 8) and below four not pronounced complaints (LNB^- n = 12).