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Table 1 Baseline and follow-up characteristics of HIV-infected women in the MTCT-Plus program (N = 290).

From: Incidence and risk factors of severe adverse events with nevirapine-based antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan, Côte d'Ivoire

At initiation of treatment

 

Period at HAART initiation

 

   Pregnant/non pregnant, n (%)

125/165 (43/57)

Exposed women to PMTCT

 

   Exposed/no exposed, n (%)

153/137 (53/47)

Age, years, median [IQR]

29 [26-33]

   >29 years

137 (47)

Body mass index, Kg/m2 [IQR]

22.3 [20.1-25.3]

   >18.5 *

250 (86)

WHO clinical stage, n (%)

 

   1

33 (11)

   2

127 (44)

   3

117 (40)

   4

13 (5)

CD4 counts, cells/mm3 [IQR]

186 [124-266]

   >250

88 (30)

Co-trimoxazole, n (%)

287 (99)

Haemoglobin level, g/l, median [IQR]

9.8 [9-11]

   ≤9.8

150 (52)

Neutrophil count, mm3, median [IQR]

2639 2639 [1911-3712]

   <1500

28 (10)

HAART regimen, n (%)

 

   ZDV/3TC/NVP

265 (91)

   d4T/3TC/NVP

25 (9)

Alanine aminotransferase, UI, median [IQR]

15 [11-24]

   <31 IU/L*

240 (83)

Aspartate aminotransférase, UI, median [IQR]

24 [19-31]

   <32 IU/L*

235 (81)

Follow-up

 

Cumulative, person-months

6388

Per patient, months, median [IQR]

25 [14-30]

Status on study termination

 

   Dead, n (%)

16 (6)

   Lost to follow-up, n (%)

7 (2)

   Alive, n (%)

267 (92)

  1. HAART: Highly active antiretroviral therapy; PMTCT: prevention to mother-to-child transmission; WHO: World Health Organization; IQR: interquartile range; ZDV: zidovudine; 3TC: lamivudine; NVP: nevirapine; d4T: stavudine; ALT: alanine aminotransferase; AST: aspartate aminotransferase; IU: International unity;
  2. * upper limit of normal