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Table 1 MIC distributions for various antimicrobials tested from Shenyang in China

From: Pharmacokinetic-pharmacodynamic profiling of four antimicrobials against Gram-negative bacteria collected from Shenyang, China

Species(no.) or antibiotic %S % of isolates susceptible at MIC(μg/ml) MIC50 MIC90 MIC range
   0.006 0.01 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 64 128 256    
E.coli (414)                   
MEM 99.8 94.4 1.7 1.5 1 0.5 0.7 0 0 0.2 0 0 0 0 0 0 0 0.03 0.032 .03 - 8
IPM 99.8 17.9 11.5 21.5 43.3 4.6 0.5 0.5 0 0.2 0 0 0 0 0 0 0 0.125 0.25 .03 - 16
FEP 69.4 12.7 1.3 2.5 4.1 16.7 5.3 2.7 9 15.3 12.1 8.3 4.4 2.4 1.7 1.5 0 4 32 .03 - 512
TZP 70.5 0.5 0 0 0.2 0.5 1 7.9 19 24.1 16.9 10.2 9.9 3 2.2 4.2 0 8 64 .03 - 512
LVX 30.8 6.8 3 1.2 8.2 5.7 5 1 7.4 18.6 23.3 14.4 5 0.2 0.2 0 0 8 32 .03 - 256
K.pneumoniae (236)                   
MEM 99.6 4.7 50.4 34.8 4.9 1.8 0.4 0.9 1.3 0.4 0 0.4 0 0 0 0 0 0.03 0.125 .015 - 16
IPM 97.8 0 0 0.6 13.1 42.2 15.5 2.5 14.9 11.2 0 0 0 0 0 0 0 0.25 2 .03 - 32
FEP 62.3 0 3 13 15.2 3.9 3.5 3.5 7.8 8.2 4.3 10.4 9.5 4.3 4.3 1.3 7.8 4 128 .03 - 512
TZP 44.6 0 0 0 0 0 0 0 1.4 11.6 19.2 12.5 21 18.3 6.7 7.1 2.2 32 128 2 - 512
LVX 64.5 0 23.8 7.9 2.6 3.9 4.8 11 11 4.8 7 8.8 7.5 5.7 1.3 0.4 0 1 32 .03 - 256
E.cloacae (40)                    
MEM 97.5 0 0 90 0 0 5 2.5 0 0 0 0 2.5 0 0 0 0 0.03 0.032 .03 - 16
IPM 97.5 0 0 12.5 50 0 17.5 7.5 10 0 0 2.5 0 0 0 0 0 0.06 1 .03 - 8
FEP 67.5 0 0 27.5 7.5 7.5 2.5 0 10 2.5 7.5 2.5 10 12.5 5 2.5 2.5 1 32 .03 - 256
TZP 60 0 0 0 0 0 0 0 2.5 10 22.5 7.5 17.5 7.5 2.5 5 25 16 256 1 - 512
LVX 70 0 0 57.5 7.5 0 2.5 0 2.5 0 2.5 2.5 7.5 15 2.5 0 0 0.03 32 .03 - 64
P.aeruginosa (281)                   
MEM 56.8 0 0 1.5 4.1 7 10 13 9.2 4.4 7.4 12.5 20.3 4.4 3 2.9 0 4 32 .03 - 128
IPM 46.5 0 0 1.1 1.1 0.4 0.7 4.1 18 10 11.4 14.8 8.5 19.9 5.2 3 2.1 8 64 .03 - 512
FEP 45.9 0 0 1.5 0 0 0 1.1 6.3 8.5 9.6 18.9 20.7 11.9 8.1 7.8 5.6 16 128 .03 - 512
TZP 43.7 0 0 0.4 0 0 0 0.7 0 1.5 3.7 12.2 8.9 6.7 9.6 10 46 128 256 .03 - 512
LVX 56.1 0 0 5.9 1.1 9.6 15.1 8.9 11 4.4 7.7 14.8 11.4 5.5 2.6 1.5 0.4 1 16 .03 - 256
A.baumannii (115)                    
MEM 37.8 0 0 4.2 7.2 5.2 6.1 7.1 6.1 1 1 2 5.1 30.6 11.2 12.2 1 32 128 .03 - 256
IPM 35.7 0 0 2 7.1 8.2 3.1 4.1 6.1 4.1 1 5.1 8.2 23.5 21.4 5.1 1 32 64 .03 - 256
FEP 19.8 0 0 0 0 0 1.9 0 2.7 3.6 8.1 3.6 16.2 7.2 9 22.5 25 64 256 .25 - 512
TZP 17.3 0 0 2 0 0 1.1 0 0 2 0 8.2 4.1 0 1 3.1 79 256 256 .03 - 512
LVX 48.7 0 0 14.8 0.9 2.6 0.9 3.5 3.5 22.6 27 12.2 7 5 0 0 0 4 16 .03 - 32
  1. MEM Meropenem; IPM Imipenem; FEP Cefepime; TZP Piperacillin/tazobactam; LVX Levofloxacin
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