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Table 2 Univariate analysis of in-hospital-mortality: patient characteristics and etiology.

From: Prognostic factors in left-sided endocarditis: results from the andalusian multicenter cohort

Variable

 

Alive

N = 497

Deaths

N = 208

RR

95% CI

p

Age (years)

Mean ± SD

51.6 ± 17

58.8 ± 16

-

-

<0.001

Gender

Male

345 (71)

141 (29)

1.07

0.76-1.52

0.367

 

Female

152 (69.4)

67 (30.6)

   

Period

1984-1995

196 (74.5)

67 (25.5)

1.25

0.97-1.60

0.070

 

1996-2006

301 (68.1)

141 (31.9)

   

Hospital

Tertiary

451 (69.3)

200(30.7)

2.07

1.08-3.96

0.008

 

Community

46 (85.2)

8 (14.8)

   

Nosocomial

Yes

55 (53.4)

48 (46.6)

1.75

1.37-2.24

<0.001

 

No

442 (73.4)

160 (26.6)

   

Comorbidity

Yes

259 (64.4)

143 (35.6)

1.65

1.28-2.13

<0.001

 

No

238 (78.8)

65 (21.5)

   

Charlson's index

Mean ± SD

1.56 ±

2,50 ±

  

<0.001

  

2.15

2.42

   

Diabetes mellitus

Yes

24 (68.8)

11 (31.4)

1.06

0.64-1.76

0.464

 

No

473 (70.6)

197 (29.4)

   

Chronic renal insufficiency

Yes

14 (58.3)

10 (41.7)

1.43

0.88-2.33

0.184

 

No

483 (70.9)

198 (29.1)

   

Chronic liver

Yes

17 (53.1)

15 (46.9)

1.63

1.10-2.40

0.027

Disease

No

480 (71,3)

193 (28,7)

   

Valve involved

Aortic

223 (71.9)

118 (29.3)

1.02

0.81-1.28

0.456

 

Mitral

274 (69.3)

90 (29.1)

   

>1 valve involved

Yes

49 (64.5)

27 (35.5)

1.23

0.89-1.71

0.223

 

No

448 (71,2)

181 (28,8)

   

Valve type

Prosthetic

104 (60.8)

67 (39.2)

1.48

1.17-1.87

0.001

 

Native

393 (73.6)

141 (26.4)

   

Prosthetic type

Early

33 (47.8)

36 (52.2)

1.93

1.48-2.50

<0.001

 

Late

464 (73)

172 (27)

   

S. aureus

Yes

70 (51.1)

67 (48.7)

1.96

1.57-2.46

<0.001

 

No

427 (75.2)

141 (24.8)

   

S. viridans group

Yes

140 (89.7)

16 (10.3)

0.29

0.18-0.47

<0.001

 

No

357 (65)

192 (35)

   

Coagulase-negative Staphylococci

Yes

64 (62.7)

38 (37.3)

1.32

0.99-1.75

0.040

 

No

433 (71.8)

170 (28.2)

   

Enterococcus spp.

Yes

52 (66.7)

26 (33.3)

1.14

0.1-1.60

0.254

 

No

445 (71)

182 (29)

   

S. agalactiae

Yes

7 (46.7)

8 (53.3)

1.84

1.12-2.99

0.044

 

No

490 (71)

200 (29)

   

Fungal

Yes

2 (22.2)

7 (77.8)

2.69

1.86-3.89

0.004

 

No

495 (71.1)

301 (28.9)

   
  1. Data are expressed as number of cases (%) except when indicated.