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Table 2 Seroconversion during and post-prophylaxis in the study population

From: Seroconversion and asymptomatic infections during oseltamivir prophylaxis against Influenza A H1N1 2009

  Overall
(n = 237)
Outbreak A
(n = 149)
Outbreak B
(n = 42)
Outbreak C
(n = 46)
Date of 1st blood sample 23 Jun-16 Jul 10 23 Jun 10 9 Jul 10 16 Jul 10
Date of 2nd blood sample 13 Jul-6 Aug 10 13 Jul 10 30 Jul 10 6 Aug 10
Date of 3rd blood sample 21-25 Aug 10 21 Aug 10 25 Aug 10 25 Aug 10
Seroconversion during prophylaxis (second vs first samples)*     
   Total 16/226 (7.1%) 10/141 (7.1%) 4/40 (10%) 2/45 (4.4%)
   Symptomatic 8/226 (3.5%) 3/141 (2.1%) 3/40 (7.5%) 2/45 (4.4%)
   Asymptomatic (and RT-PCR negative) 8/226 (3.5%) 7/141 (5.0%) 1/40 (2.5%) 0/45 (0.0%)
Overall infection rate during outbreak (serological and index cases) 27/237 (11.4%) 18/149 (12.1%) 6/42 (14.3%) 3/46 (6.5%)
Seroconversion post-prophylaxis (third vs second samples)     
   Total 23/190 (12.1%) 16/115 (13.9%) 1/34 (2.9%) 6/41 (14.6%)
   Symptomatic 4/190 (2.1%) 2/115 (1.7%) 1/34 (2.9%) 1/41 (2.4%)
   Asymptomatic 19/190 (10.0%) 14/115 (12.2%) 0/34 (0.0%) 5/41 (12.2%)
  1. *Excluding index cases