Nosocomial methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in Taiwan: Mortality analyses and the impact of vancomycin, MIC = 2 mg/L, by the broth microdilution method

Table 3 Univariate and multivariate analysis of risk factors associated with mortality of patients with nosocomial MRSA bacteremia using Cox regression

Characteristic	Univariate HR	95% CI	p-value	Multivariate HR	95% CI	p-value
High vancomycin MIC	2.20	1.13-4.27	0.021	2.39	1.20-4.79	0.014
Malignancy	2.73	1.45-5.11	0.002	2.09	0.99-4.43	0.053
Pneumonia	1.74	0.92-3.27	0.088	2.27	1.17-4.40	0.016
Cardiothoracic surgery	1.86	0.82-4.20	0.139	4.38	1.74-11.04	0.002
Charlson score	1.27	1.10-1.46	0.001	1.24	1.07-1.45	0.005
Endocarditis	2.24	2.24-6.31	0.126
Bedridden	2.63	1.03-6.71	0.044
Cerebrovascular disease	2.06	0.81-5.27	0.131
ICU admission	2.05	1.07-3.90	0.029

Note: Variables with a p < 0.2 in the univariate analyses were included in the subsequent multivariate Cox proportional hazards regression model.

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