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Table 3 Univariate and multivariate analysis of risk factors associated with mortality of patients with nosocomial MRSA bacteremia using Cox regression

From: Nosocomial methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in Taiwan: Mortality analyses and the impact of vancomycin, MIC = 2 mg/L, by the broth microdilution method

Characteristic Univariate HR 95% CI p-value Multivariate HR 95% CI p-value
High vancomycin MIC 2.20 1.13-4.27 0.021 2.39 1.20-4.79 0.014
Malignancy 2.73 1.45-5.11 0.002 2.09 0.99-4.43 0.053
Pneumonia 1.74 0.92-3.27 0.088 2.27 1.17-4.40 0.016
Cardiothoracic surgery 1.86 0.82-4.20 0.139 4.38 1.74-11.04 0.002
Charlson score 1.27 1.10-1.46 0.001 1.24 1.07-1.45 0.005
Endocarditis 2.24 2.24-6.31 0.126    
Bedridden 2.63 1.03-6.71 0.044    
Cerebrovascular disease 2.06 0.81-5.27 0.131    
ICU admission 2.05 1.07-3.90 0.029    
  1. Note: Variables with a p < 0.2 in the univariate analyses were included in the subsequent multivariate Cox proportional hazards regression model.