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Table 2 Infection syndrome, treatment and outcome of nosocomial bacteremia in patients infected with high MIC MRSA or low MIC MRSA

From: Nosocomial methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in Taiwan: Mortality analyses and the impact of vancomycin, MIC = 2 mg/L, by the broth microdilution method

Syndrome & treatment

Vancomycin MIC < 2 N = 97 Number of patients (%)

Vancomycin MIC = 2 N = 26 Number of patients (%)

p-value a

Syndrome

   

Primary bacteremia

18 (18.6)

5 (19.2)

0.938

Pneumonia

32 (33.0)

9 (34.6)

0.876

Catheter related infection

40 (41.2)

12 (46.2)

0.652

Prosthesis

6(6.2)

0 (0)

0.341

Infective endocarditis

6 (6.2)

0 (0)

0.341

Treatment

   

Empirical glycopeptide use within 48 hours

71 (73.2)

19 (73.1)

1.000

Vancomycin trough level (mg/L)

14.9 ± 7.6 (n = 47)

13.5 ± 4.9 (n = 12)

0.176

Vancomycin trough level > 10 mg/L in first week

34 (72.3)

9 (75.0)

1.000

With a DNR orderb

26 (26.8)

11 (42.3)

0.151

Outcome

   

2 week death

14 (14.4)

8 (30.8)

0.081

30 days death

27 (27.8)

13 (50.0)

0.057

  1. a: p-value calculated using a χ2 test or Fisher's exact test
  2. b: Do not resuscitate