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Table 2 Hazard ratios (HR) by smoking status on total cohort, and on sub-cohort with self-reported TB history for TB mortality

From: The reduction of tuberculosis risks by smoking cessation

 

Total cohort (486,341)

Sub-cohort who responded to TB history question

      

self reported TB history (-)

414,460

Self reported TB history (+)

5,036

Self reported

TB history (-)

414,460

Self reported

TB history (+)

5,036

 

N

HR†

(95%C.I.)

HR‡

(95%C.I.)

N

HR§

N

HR§

(95%C.I.)

HR||

(95%C.I.)

HR||

(95%C.I.)

Hazard ratio- TB deaths

TB deaths

(77)

    

64

1

13

5.90*

(3.1~11.2)

    

   Never smoker**

8

1

-

1

-

3

-

5

4.75*

(1.9~12.0)

1

-

29.47*

(6.9~125.2)

   Current smoker**

21

4.19*

(1.8~9.7)

3.37*

(1.4~8.1)

17

-

4

10.10*

(3.3~30.8)

8.56*

(2.5~29.8)

44.02*

(9.6~201.6)

   Ex-smoker**

6

1.90

(0.6~5.6)

2.02

(0.7~6.0)

3

-

3

5.51*

(1.6~18.4)

3.03

(0.6~15.3)

29.25*

(5.7~149.0)

   Ever smoker**

27

3.97*

(1.9~8.4)

2.62*

(1.2~5.9)

         

   Current smoker**

              

<half a pack/day

10

5.35*

(2.0~14.1)

3.70*

(1.4~10.0)

         

≧half a pack/day

11

2.88*

(1.1~7.5)

1.84

(0.7~5.0)

         

<10 years of smoking

1

3.01

(0.4~25.0)

2.38

(0.3~20.1)

         

≧10 years of smoking

20

3.74*

(1.6~8.9)

2.44

(1.0~6.0)

         

<15 pack-year

4

3.51*

(1.0~12.1)

2.54

(0.7~8.9)

         

≧15 pack-year

17

3.83*

(1.6~9.3)

2.46

(1.0~6.2)

         
  1. *: p < 0.05 † : HR adjusted for age and gender, with nonsmokers as reference group;
  2. ‡ : HR adjusted for age, gender, education, drinking, BMI and DM history with nonsmokers as reference group
  3. § : HR adjusted for age, gender, education, drinking, BMI and DM history, with those with TB history (-) as reference group;
  4. ||: HR: adjusted for age, gender, education, drinking, BMI and DM history, with those nonsmokers with TB history (-) as reference group
  5. ** The actual number of subjects with smoking history was used to calculate HRs