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Table 2 Hazard ratios (HR) by smoking status on total cohort, and on sub-cohort with self-reported TB history for TB mortality

From: The reduction of tuberculosis risks by smoking cessation

  Total cohort (486,341) Sub-cohort who responded to TB history question
       self reported TB history (-)
414,460
Self reported TB history (+)
5,036
Self reported
TB history (-)
414,460
Self reported
TB history (+)
5,036
  N HR† (95%C.I.) HR‡ (95%C.I.) N HR§ N HR§ (95%C.I.) HR|| (95%C.I.) HR|| (95%C.I.)
Hazard ratio- TB deaths TB deaths
(77)
     64 1 13 5.90* (3.1~11.2)     
   Never smoker** 8 1 - 1 - 3 - 5 4.75* (1.9~12.0) 1 - 29.47* (6.9~125.2)
   Current smoker** 21 4.19* (1.8~9.7) 3.37* (1.4~8.1) 17 - 4 10.10* (3.3~30.8) 8.56* (2.5~29.8) 44.02* (9.6~201.6)
   Ex-smoker** 6 1.90 (0.6~5.6) 2.02 (0.7~6.0) 3 - 3 5.51* (1.6~18.4) 3.03 (0.6~15.3) 29.25* (5.7~149.0)
   Ever smoker** 27 3.97* (1.9~8.4) 2.62* (1.2~5.9)          
   Current smoker**               
<half a pack/day 10 5.35* (2.0~14.1) 3.70* (1.4~10.0)          
half a pack/day 11 2.88* (1.1~7.5) 1.84 (0.7~5.0)          
<10 years of smoking 1 3.01 (0.4~25.0) 2.38 (0.3~20.1)          
10 years of smoking 20 3.74* (1.6~8.9) 2.44 (1.0~6.0)          
<15 pack-year 4 3.51* (1.0~12.1) 2.54 (0.7~8.9)          
15 pack-year 17 3.83* (1.6~9.3) 2.46 (1.0~6.2)          
  1. *: p < 0.05 † : HR adjusted for age and gender, with nonsmokers as reference group;
  2. ‡ : HR adjusted for age, gender, education, drinking, BMI and DM history with nonsmokers as reference group
  3. § : HR adjusted for age, gender, education, drinking, BMI and DM history, with those with TB history (-) as reference group;
  4. ||: HR: adjusted for age, gender, education, drinking, BMI and DM history, with those nonsmokers with TB history (-) as reference group
  5. ** The actual number of subjects with smoking history was used to calculate HRs