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Table 1 Manufacturing information of oxacillin products included in the study (11 generics plus the innovator).

From: In vitro and in vivo comparison of the anti-staphylococcal efficacy of generic products and the innovator of oxacillin

OXACILLIN (OXA) PRODUCTS

BATCH

MANUFACTURER

DISTRIBUTOR

PERFORMED TESTS

OXA-BMS (innovator)

EL059

EG187

EF109

EF372

ED259

Bristol-Myers Squibb de Mexico.

Bristol-Myers Squibb

MA, MIC&MBC, NMTIM

OXA-BLA

A 4602

B 4603

Vitrofarma SA, Bogota, Colombia

Laboratorios Blaskov

MA, MIC&MBC, NMTIM

OXA-CAR

309V1104

378V0705

Farmacologica SA, Bogota, Colombia

Carlon Ltda

MA, MIC&MBC, NMTIM

OXA-COL

0010202

05103

Farmacologica SA, Bogota, Colombia

Colpharma Ltda

MA, MIC&MBC, NMTIM

OXA-EXP*

OX 010462

Farmacologica SA Bogota, Colombia

Laboratorios Expopharma

MA, NMTIM

OXA-MEM

110291

050239

090281

Vitrofarma SA, Bogota, Colombia

Memphis Products

MA, MIC&MBC, NMTIM

OXA-OPH

080267

060249

Vitrofarma SA, Bogota, Colombia

Laboratorios Farmaceuticos Ophalac

MA, MIC&MBC, NMTIM

OXA-PEN*

20275

30417

Farmacologica SA, Bogota, Colombia

Pentacoop SA

MA, MIC&MBC, NMTIM

OXA-QIM

6400702

Vitrofarma SA, Bogota, Colombia

Quimicol

MIC&MBC, NMTIM

OXA-SCA

OX-010462

Farmacologica SA, Bogota, Colombia

Farmionni Scalpi S.A.

MA, NMTIM

OXA-SER

OX-010508

Farmacologica SA Bogota, Colombia

Serpharma SA

MIC&MBC, NMTIM

OXA-VIT

120198

090281

110291

Vitrofarma SA, Bogota, Colombia

Vitalis

MA, MIC&MBC, NMTIM

  1. Abbreviators: MA: microbiological assay; MIC&MBC: minimal inhibitory concentration and minimal bactericidal concentration; NMTIM: neutropenic mouse thigh infection model. *The data from one experiment involving these two generic products and the innovator had to be excluded from the analysis due to heavy contamination of agar plates containing thigh homogenates that prevented reliable colony counting