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Table 2 Mutation patterns following from the GenoType ® MTBDRplus assay.

From: Validation of the GenoType®MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam

rpoBmutations

katGmutations

inhAmutations

Frequency

Proportion

D516V

S315T1

--

1

0.9

D516V

unknown *

--

1

0.9

D516V

--

C15T

1

0.9

H526D

S315T1

--

1

0.9

H526Y

S315T1

--

5

4.6

S531L

unknown *

--

2

1.8

S531L

S315T1

C15T

1

0.9

S531L

S315T1

--

16

14.6

S531L

S315T2

--

1

0.9

S531L

--

C15T

4

3.6

S531L

--

--

2

1.8

H526Y + S531L

--

--

1

0.9

unknown *

S315T1

--

13

11.8

unknown *

--

--

3

1.8

unknown *

unknown *

C15T

1

0.9

unknown *

--

C15T

1

0.9

--

S315T1

--

1

0.9

--

--

C15T

1

0.9

Total number of strains with any mutations

56

50.9

--

--

--

54

49.1

Total number of strains

110

100

  1. * unknown mutation: no hybridization to one or more of the wild type probes nor to any of the mutation probes.