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Table 2 Mutation patterns following from the GenoType ® MTBDRplus assay.

From: Validation of the GenoType®MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam

rpoBmutations katGmutations inhAmutations Frequency Proportion
D516V S315T1 -- 1 0.9
D516V unknown * -- 1 0.9
D516V -- C15T 1 0.9
H526D S315T1 -- 1 0.9
H526Y S315T1 -- 5 4.6
S531L unknown * -- 2 1.8
S531L S315T1 C15T 1 0.9
S531L S315T1 -- 16 14.6
S531L S315T2 -- 1 0.9
S531L -- C15T 4 3.6
S531L -- -- 2 1.8
H526Y + S531L -- -- 1 0.9
unknown * S315T1 -- 13 11.8
unknown * -- -- 3 1.8
unknown * unknown * C15T 1 0.9
unknown * -- C15T 1 0.9
-- S315T1 -- 1 0.9
-- -- C15T 1 0.9
Total number of strains with any mutations 56 50.9
-- -- -- 54 49.1
Total number of strains 110 100
  1. * unknown mutation: no hybridization to one or more of the wild type probes nor to any of the mutation probes.