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Table 2 Comparison between the clinical characteristics and laboratory test abnormalities of patients with pneumonia and 2009 H1N1 influenza who were admitted to an ICU and patients who were not admitted to an ICU in the First Affiliated Hospital of China Medical University during November 4 to December 31, 2009.

From: Factors associated with death in hospitalized pneumonia patients with 2009 H1N1 influenza in Shenyang, China

Clinical characteristic or laboratory test abnormality

ICU

Non-ICU

P

 

data

n

data

n

 

Medical Condition (no. (%))

16 (53)

30

7 (18)

38

0.003#

Cigarette index ≥ 400(no. (%))

5 (17)

30

4 (10)

38

0.458

BMI ≥ 24 (no. (%))

23(77)

30

19(50)

38

0.025#

   BMI 24-27.9

10 (33)

30

10 (32)

38

0.528

   BMI ≥ 28

13 (43)

30

9 (24)

38

0.085

Median age

41 (18-63)

30

41 (18-66)

38

0.990

Interval from onset of illness to initiation of antiviral therapy, in days

7 (4-12)

30

7 (2-15)

38

0.551

Lymphcyto count (×109/L)

0.58 (0.02-4.34)

30

1.065 (0.31-2.48)

38

<0.0005**

LDH (U/L)

1097.5 (218-4340)

30

688 (180-2250)

37

0.005**

CK (U/L)

220 (23-4188)

30

161 (20-2712)

37

0.313

AST (U/L)

66 (12-229)

30

41.5 (13-339)

38

0.107

ALT (U/L)

45.5 (15-188)

30

43.5 (11-204)

38

0.537

Alb (g/L)

28.95 (18-42)

30

37 (9.6-51)

38

<0.0005**

CRP (mg/mL)

2.66 (0.25-29.7)

27

1.23 (0.1-10.2)

38

0.024**

CD4 T cell count (/μL)

232 (29-1892)

28

651 (128-1607)

36

<0.0005**

CD8 T cell count (/μL)

166.5 (23-1109)

28

406 (85-1113)

36

<0.0005**

CD3 T cell count (/μL)

465 (57-3046)

28

1148.5 (216-2496)

36

<0.0005**

  1. **..... Statistically significant with the use of a non-parametric Mann-Whitney U test; #..... Statistically significant with the use of a chi-square test or Fisher's exact test test
  2. BMI: Body Mass Index; LDH: lactic dehydrogenase; CK: creatine kinase; AST: glutamic-oxaloacetic transaminase; ALT: glutamic alanine aminotransferase; Alb: albumin; CRP: C reactive protein.